PEP0017

Invitrogen™ Mouse ICAD Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0017-Each-of-1 In Stock ₹ 16,247.84

PEP0017 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

13347

Purification Method

purified

Common Name

Mouse ICAD

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Mouse

Accession Number

O54786

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

Dffa

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • ICAD Synthetic Peptide, PEP-0017, from Invitrogen
  • ICAD is the inhibitor of caspase-3-activated DNase which is a substrate that controls nuclear apoptosis
  • ICAD has two isoforms: a functional isoform of 45kDa, ICAD-L/DNA fragmentation factor (DFF) 45; and a 35kDa isoform, ICAD-S/DFF35
  • Although both ICAD-L and ICAD-S can bind and inhibit CAD, only ICAD-L was reported to be functional
  • ICAD is cleaved to be inactivated and allow caspase-activated DNase (CAD) to execute nuclear internucleosomal apoptotic DNA fragmentation
  • In non-apoptotic cells, CAD is complexed with its inhibitor, ICAD
  • The activation of the CAD/ICAD complex occurs through the caspase 3-mediated cleavage of ICAD at residues 117 and 224, which results in three ICAD fragments that are then released from CAD
  • In addition to its DNase inhibitory activity, ICAD acts as a CAD specific folding chaperone
  • There are recent reports that ICAD is a potential target for restoring a normal apoptotic signal transduction pathway in colon and brain cancer cells
  • Two alternatively spliced transcript variants encoding distinct isoforms have been found for the ICAD gene
  • This peptide corresponds to 20 amino amino terminus of mouse ICAD.PEP-0017 can be used as a blocking peptide with polyclonal antibody PA5-19889.

Compare Similar Items

Show Difference

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Invitrogen™

PEP0017

--


Gene ID (Entrez):
13347

Purification Method:
purified

Common Name:
Mouse ICAD

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
O54786

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
Dffa

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0018

--


Gene ID (Entrez):
13347

Purification Method:
purified

Common Name:
Mouse ICAD

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
O54786

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
Dffa

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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Invitrogen™

PEP0019

--


Gene ID (Entrez):
69719

Purification Method:
purified

Common Name:
Mouse CAD

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
B2RQC6

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
Cad

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

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PEP002

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Gene ID (Entrez):
2908

Purification Method:
purified

Common Name:
Human Glucocorticoid Receptor (aa 245-259)

Content And Storage:
-20°C. Avoid freeze-thaw cycles.

Format:
Lyophilized

For Use With (Application):
Control

Lyophilized:
Yes

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
P04150

Concentration:
0.5 mg/mL

Description:
Synthetic Peptide

Formulation:
peptide with no preservative

Gene Symbol:
NR3C1

Preservative:
No preservative

Quantity:
50 μg

Storage Buffer:
__