PEP0201

Invitrogen™ Human TAK1 Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0201-Each-of-1 In Stock ₹ 16,247.84

PEP0201 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

6885

Purification Method

purified

Common Name

Human TAK1

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Human

Accession Number

O43318

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

MAP3K7

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • TAK1 Synthetic Peptide, PEP-0201, from Invitrogen
  • TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan
  • This peptide corresponds to 14 amino acids near the amino terminus of human TAK1 (NT).PEP-0201 can be used as a blocking peptide with polyclonal antibody PA5-20083.

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Invitrogen™

PEP0201

--


Gene ID (Entrez):
6885

Purification Method:
purified

Common Name:
Human TAK1

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
O43318

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
MAP3K7

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0205

--


Gene ID (Entrez):
3661

Purification Method:
purified

Common Name:
Human IRF3

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q14653

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IRF3

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0206

--


Gene ID (Entrez):
3394

Purification Method:
purified

Common Name:
Human IRF8

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q02556

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
IRF8

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Img

Invitrogen™

PEP0207

--


Gene ID (Entrez):
10018

Purification Method:
purified

Common Name:
Human Bim

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
O43521

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
BCL2L11

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS