PEP0535

Invitrogen™ Human PTEN Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0535-Each-of-1 In Stock ₹ 16,247.84

PEP0535 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

5728

Purification Method

purified

Common Name

Human PTEN

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Gene Symbol

PTEN

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

Species

Human

Accession Number

P60484

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Alias

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MMAC1, TEP1, Phosphatase and tensin homolog

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

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Description

  • PTEN Synthetic Peptide, PEP-0535, from Invitrogen
  • PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
  • The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
  • It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
  • Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
  • PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
  • PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
  • Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
  • The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability
  • PEP-0535 can be used as a blocking peptide with polyclonal antibody PA5-20418.

Compare Similar Items

Show Difference

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Invitrogen™

PEP0535

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Gene ID (Entrez):
5728

Purification Method:
purified

Common Name:
Human PTEN

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Gene Symbol:
PTEN

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Species:
Human

Accession Number:
P60484

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Alias:
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MMAC1, TEP1, Phosphatase and tensin homolog

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Img

Invitrogen™

PEP0536

--


Gene ID (Entrez):
5048

Purification Method:
purified

Common Name:
Human LIS1

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Gene Symbol:
PAFAH1B1

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Species:
Human

Accession Number:
P43034

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Alias:
__

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

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PEP0537

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Gene ID (Entrez):
3798

Purification Method:
purified

Common Name:
Human Kinesin 5A

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Gene Symbol:
KIF5A

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Species:
Human

Accession Number:
Q12840

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Alias:
__

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Img

Invitrogen™

PEP0538

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Gene ID (Entrez):
3798

Purification Method:
purified

Common Name:
Human Kinesin 5A

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Gene Symbol:
KIF5A

Preservative:
0.02% sodium azide

Quantity:
50 μg

Storage Buffer:
PBS

Species:
Human

Accession Number:
Q12840

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Alias:
__

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only