PEP121

Invitrogen™ Mouse MECP2 (aa 469-486) Synthetic Peptide

Manufacturer: Invitrogen™

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Gene ID (Entrez)

17257

Purification Method

purified

Common Name

Mouse MECP2 (aa 469-486)

Content And Storage

-20°C. Avoid freeze-thaw cycles.

Format

Lyophilized

For Use With (Application)

Control

Lyophilized

Yes

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Mouse

Accession Number

Q9Z2D6

Concentration

0.5 mg/mL

Description

Synthetic Peptide

Formulation

peptide with no preservative

Gene Symbol

Mecp2

Preservative

No preservative

Quantity

50 μg

Sequence

C-P(469)-N-R-E-E-P-V-D-S-R-T-P-V-T-E-R-V-S(486)

Description

  • Mouse MeCP2 (residues 469-486) Synthetic Peptide, PEP-121, from Invitrogen
  • MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
  • MECP2 is capable of binding specifically to methylated DNA
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
  • MECP2 can also repress transcription from methylated gene promoters
  • In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
  • MECP2 is dispensible in stem cells, but is essential for embryonic development
  • MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females
  • PEP-121 is a 18 amino acid synthetic peptide whose sequences are derived from amino acids 469-486 of mouse MeCP2 protein with a amino-terminal cysteine added for carrier protein conjugation
  • The sequence of this peptide is (amino to carboxy terminus): C-P (469)-N-R-E-E-P-V-D-S-R-T-P-V-T-E-R-V-S (486)PEP-121 may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse MeCP2, catalog &Num PA1-888
  • Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (∽70-fold) for competitive inhibition of antibody-protein binding reactions.Reconstitute with 0.1 mL of distilled water.

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Invitrogen™

PEP121

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Gene ID (Entrez):
17257

Purification Method:
purified

Common Name:
Mouse MECP2 (aa 469-486)

Content And Storage:
-20°C. Avoid freeze-thaw cycles.

Format:
Lyophilized

For Use With (Application):
Control

Lyophilized:
Yes

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Mouse

Accession Number:
Q9Z2D6

Concentration:
0.5 mg/mL

Description:
Synthetic Peptide

Formulation:
peptide with no preservative

Gene Symbol:
Mecp2

Preservative:
No preservative

Quantity:
50 μg

Sequence:
C-P(469)-N-R-E-E-P-V-D-S-R-T-P-V-T-E-R-V-S(486)

Img

Invitrogen™

PEP1210

--


Gene ID (Entrez):
347730

Purification Method:
purified

Common Name:
Human LRRTM1

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
Q86UE6

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
LRRTM1

Preservative:
0.02% sodium azide

Quantity:
50 μg

Sequence:
__

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Invitrogen™

PEP1211

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Gene ID (Entrez):
26045

Purification Method:
purified

Common Name:
Human LRRTM2

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
O43300

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
LRRTM2

Preservative:
0.02% sodium azide

Quantity:
50 μg

Sequence:
__

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Invitrogen™

PEP1213

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Gene ID (Entrez):
9683

Purification Method:
purified

Common Name:
Human N4BP1

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
O75113

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
N4BP1

Preservative:
0.02% sodium azide

Quantity:
50 μg

Sequence:
__