PEP253
Human ATR (aa 92-107), Synthetic Peptide, Invitrogen™
Manufacturer: Thermo Scientific
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Gene ID (Entrez)
545
Purification Method
purified
Common Name
Human ATR (aa 92-107)
Content And Storage
-20°C. Avoid freeze-thaw cycles.
Format
Lyophilized
For Use With (Application)
Control
Lyophilized
Yes
Product Type
Peptide
Regulatory Status
RUO - research use only
Species
Human
Accession Number
Q13535
Concentration
0.5 mg/mL
Description
Synthetic Peptide
Formulation
peptide with no preservative
Gene Symbol
ATR
Preservative
No preservative
Quantity
50 μg
Sequence
L-M-K-L-T-E-D-R-E-Q-I-R-Q-G-L-E-C
Related Products
Description
- Human ATR/TEM8 (residues 92-107) Synthetic Peptide, PEP-253, from Invitrogen
- The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8)
- This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis
- However, it also acts as the receptor for anthrax toxin
- Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF)
- This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis
- PEP-253 is a 17 amino acid synthetic peptide corresponding to amino acid residues 92-107 from human ATR/TEM8
- The sequence of this peptide is (amino to carboxy terminus): L-M-K-L-T-E-D-R-E-Q-I-R-Q-G-L-E-C.This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog &Num PA1-602
- Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (∽70-fold) for competitive inhibition of antibody-protein binding reactions.Reconstitute with 0.1 mL of distilled water.
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Gene ID (Entrez): 545
Purification Method: purified
Common Name: Human ATR (aa 92-107)
Content And Storage: -20°C. Avoid freeze-thaw cycles.
Format: Lyophilized
For Use With (Application): Control
Lyophilized: Yes
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Human
Accession Number: Q13535
Concentration: 0.5 mg/mL
Description: Synthetic Peptide
Formulation: peptide with no preservative
Gene Symbol: ATR
Preservative: No preservative
Quantity: 50 μg
Sequence: L-M-K-L-T-E-D-R-E-Q-I-R-Q-G-L-E-C
Gene ID (Entrez):
545
Purification Method:
purified
Common Name:
Human ATR (aa 92-107)
Content And Storage:
-20°C. Avoid freeze-thaw cycles.
Format:
Lyophilized
For Use With (Application):
Control
Lyophilized:
Yes
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Human
Accession Number:
Q13535
Concentration:
0.5 mg/mL
Description:
Synthetic Peptide
Formulation:
peptide with no preservative
Gene Symbol:
ATR
Preservative:
No preservative
Quantity:
50 μg
Sequence:
L-M-K-L-T-E-D-R-E-Q-I-R-Q-G-L-E-C
Gene ID (Entrez): 22259
Purification Method: purified
Common Name: Mouse LXR alpha (aa 35-49)
Content And Storage: -20°C. Avoid freeze-thaw cycles.
Format: Lyophilized
For Use With (Application): Control
Lyophilized: Yes
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Mouse
Accession Number: Q9Z0Y9
Concentration: 0.5 mg/mL
Description: Synthetic Peptide
Formulation: peptide with no preservative
Gene Symbol: Nr1h3
Preservative: No preservative
Quantity: 50 μg
Sequence: T35 - C - I - L - R - E - E - A - R - M - P - Q - S - T- G49
Gene ID (Entrez):
22259
Purification Method:
purified
Common Name:
Mouse LXR alpha (aa 35-49)
Content And Storage:
-20°C. Avoid freeze-thaw cycles.
Format:
Lyophilized
For Use With (Application):
Control
Lyophilized:
Yes
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Mouse
Accession Number:
Q9Z0Y9
Concentration:
0.5 mg/mL
Description:
Synthetic Peptide
Formulation:
peptide with no preservative
Gene Symbol:
Nr1h3
Preservative:
No preservative
Quantity:
50 μg
Sequence:
T35 - C - I - L - R - E - E - A - R - M - P - Q - S - T- G49
Gene ID (Entrez): 20787
Purification Method: purified
Common Name: Mouse SREBP1 (aa 32-47)
Content And Storage: -20°C. Avoid freeze-thaw cycles.
Format: Lyophilized
For Use With (Application): Control
Lyophilized: Yes
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Mouse
Accession Number: Q9WTN3
Concentration: 0.5 mg/mL
Description: Synthetic Peptide
Formulation: peptide with no preservative
Gene Symbol: Srebf1
Preservative: No preservative
Quantity: 50 μg
Sequence: M(32) - L - Q - L - I - N - N - Q - D - S - D - F - P - G - L - F(4 )
Gene ID (Entrez):
20787
Purification Method:
purified
Common Name:
Mouse SREBP1 (aa 32-47)
Content And Storage:
-20°C. Avoid freeze-thaw cycles.
Format:
Lyophilized
For Use With (Application):
Control
Lyophilized:
Yes
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Mouse
Accession Number:
Q9WTN3
Concentration:
0.5 mg/mL
Description:
Synthetic Peptide
Formulation:
peptide with no preservative
Gene Symbol:
Srebf1
Preservative:
No preservative
Quantity:
50 μg
Sequence:
M(32) - L - Q - L - I - N - N - Q - D - S - D - F - P - G - L - F(4 )
Gene ID (Entrez): 300095
Purification Method: purified
Common Name: Rat SREBP2 (aa 843-857)
Content And Storage: -20°C. Avoid freeze-thaw cycles.
Format: Lyophilized
For Use With (Application): Control
Lyophilized: Yes
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Rat
Accession Number: Q3T1I5
Concentration: 0.5 mg/mL
Description: Synthetic Peptide
Formulation: peptide with no preservative
Gene Symbol: Srebf2
Preservative: No preservative
Quantity: 50 μg
Sequence: A( 843) - I - S - W - L - Q - G - D - D - A - A -V - R - S - H(857)
Gene ID (Entrez):
300095
Purification Method:
purified
Common Name:
Rat SREBP2 (aa 843-857)
Content And Storage:
-20°C. Avoid freeze-thaw cycles.
Format:
Lyophilized
For Use With (Application):
Control
Lyophilized:
Yes
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Rat
Accession Number:
Q3T1I5
Concentration:
0.5 mg/mL
Description:
Synthetic Peptide
Formulation:
peptide with no preservative
Gene Symbol:
Srebf2
Preservative:
No preservative
Quantity:
50 μg
Sequence:
A( 843) - I - S - W - L - Q - G - D - D - A - A -V - R - S - H(857)