81271
Polymyxin B solution
1 mg/mL in H2O, analytical standard
Manufacturer: Supelco
CAS Number: 1405-20-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 ML | 81271-10-ML | In Stock | ₹ 8,086.28 |
81271 - 10 ML
In Stock
Quantity
1
Base Price: ₹ 8,086.28
GST (18%): ₹ 1,455.53
Total Price: ₹ 9,541.81
grade
analytical standard
Quality Level
100
concentration
1 mg/mL in H2O
technique(s)
HPLC: suitablegas chromatography (GC): suitable
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriafungi
application(s)
pharmaceutical (small molecule)
format
single component solution
Mode of action
cell membrane | interferes
storage temp.
2-8°C
InChI
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Polymyxin B Sulfate | Supelco | ₹ 10,435.30 | |
| | Polymyxin B sulfate | Sigma Aldrich | ₹ 46,222.75 | |
| | Polymyxin B sulfate for microbiological assay | Sigma Aldrich | ₹ 14,267.35 | |
| | Polymyxin B sulfate | Sigma Aldrich | ₹ 16,107.60 | |
| | Polymyxin B sulfate | Sigma Aldrich | ₹ 24,865.03 | |
 | Polymyxin B sulfate salt | Sigma Aldrich | ₹ 7,122.85 - ₹ 16,951.95 | |
| | Polymyxin B sulfate salt | Sigma Aldrich | ₹ 5,282.60 - ₹ 52,955.90 | |
| | Polymyxin B solution | Sigma Aldrich | ₹ 28,675.43 - ₹ 5,01,598.03 |
Description
- General description: Chemical structure: peptide
- Application: Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
- Biochem/physiol Actions: Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane. Mode of Resistance: The activity of Polymyxin B sulfate is inhibited by iron(II), Co(II), Mn(II) and Magnesium ions. Polymyxin B may also be incompaitible with other microbial agents, including amphoterecin, cephalothin sodium, cephasolin sodium and heparin sodium. Antimicrobial Spectrum: Has bactericidal action on most gram-negative bacilli, including E. Coli and on most fungi and gram-positive bacteria.
- Preparation Note: This product is concentrated at 1 mg/mL in water, and should be stored at 2-8°C.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
grade: analytical standard
Quality Level: 100
concentration: 1 mg/mL in H2O
technique(s): HPLC: suitablegas chromatography (GC): suitable
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteriafungi
application(s): pharmaceutical (small molecule)
format: single component solution
Mode of action: cell membrane | interferes
storage temp.: 2-8°C
InChI: 1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
grade:
analytical standard
Quality Level:
100
concentration:
1 mg/mL in H2O
technique(s):
HPLC: suitablegas chromatography (GC): suitable
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriafungi
application(s):
pharmaceutical (small molecule)
format:
single component solution
Mode of action:
cell membrane | interferes
storage temp.:
2-8°C
InChI:
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
grade: __
Quality Level: 100
concentration: __
technique(s): __
antibiotic activity spectrum: __
application(s): __
format: __
Mode of action: __
storage temp.: __
InChI: __
grade:
__
Quality Level:
100
concentration:
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technique(s):
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antibiotic activity spectrum:
__
application(s):
__
format:
__
Mode of action:
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storage temp.:
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InChI:
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grade: __
Quality Level: 200
concentration: __
technique(s): __
antibiotic activity spectrum: __
application(s): __
format: __
Mode of action: __
storage temp.: __
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
grade:
__
Quality Level:
200
concentration:
__
technique(s):
__
antibiotic activity spectrum:
__
application(s):
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format:
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Mode of action:
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storage temp.:
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InChI:
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
grade: analytical standardfor GPC
Quality Level: 100
concentration: __
technique(s): gel permeation chromatography (GPC): suitable
antibiotic activity spectrum: __
application(s): cleaning productscosmeticsfood and beveragespersonal care
format: neat
Mode of action: __
storage temp.: 2-8°C
InChI: __
grade:
analytical standardfor GPC
Quality Level:
100
concentration:
__
technique(s):
gel permeation chromatography (GPC): suitable
antibiotic activity spectrum:
__
application(s):
cleaning productscosmeticsfood and beveragespersonal care
format:
neat
Mode of action:
__
storage temp.:
2-8°C
InChI:
__