C4142

Capreomycin sulfate from Streptomyces capreolus

antibacterial peptide

Manufacturer: Sigma Aldrich

CAS Number: 1405-37-4

Select a Size

Pack Size SKU Availability Price
1 G C4142-1-G In Stock ₹ 43,159.28
5 G C4142-5-G In Stock ₹ 59,710.70

C4142 - 1 G

₹ 43,159.28

In Stock

Quantity

1

Base Price: ₹ 43,159.28

GST (18%): ₹ 7,768.67

Total Price: ₹ 50,927.95

Quality Level

200

form

powder

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteriamycobacteria

Mode of action

DNA synthesis | interferes

storage temp.

−20°C

SMILES string

OS(O)(=O)=O.NCCC[C@H](N)C(=O)NC[C@H]1NC(=O)[C@H](CO)NC(=O)[C@H](N)CNC(=O)[C@@H](NC(=O)\C(NC1=O)=C\NC(N)=O)[C@H]2CCNC(=N)N2

InChI

1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11+,12?,13+,15-,16-;/m0./s1

InChI key

LFFNIXQXRKNZCE-UBBQZPMLSA-N

Other Options

Image Product Name Manufacturer Price Range
PHR1716
Capreomycin Sulfate
Supelco ₹ 27,906.85

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Description

  • Application: Capreomycin is used to study bacterial ribosomal subunit interactions and translocation processes during protein synthesis. It is a second line antibiotic and is used to study multidrug-resistant tuberculosis.[1][2]
  • Biochem/physiol Actions: Capreomycin is a cyclic peptide antibiotic that is often grouped with aminoglycosides. It binds across the ribosomal interface involving 23S rRNA helix 69 (H69) and 16S rRNA helix 44 (h44).[3]
  • Preparation Note: Sparingly soluble in water.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302 + H312 + H332,H360

Precautionary Statements

P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Compare Similar Items

Show Difference

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Sigma Aldrich

C4142

antibacterial peptide...


Quality Level:
200

form:
powder

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycobacteria

Mode of action:
DNA synthesis | interferes

storage temp.:
−20°C

SMILES string:
OS(O)(=O)=O.NCCC[C@H](N)C(=O)NC[C@H]1NC(=O)[C@H](CO)NC(=O)[C@H](N)CNC(=O)[C@@H](NC(=O)\C(NC1=O)=C\NC(N)=O)[C@H]2CCNC(=N)N2

InChI:
1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11+,12?,13+,15-,16-;/m0./s1

InChI key:
LFFNIXQXRKNZCE-UBBQZPMLSA-N

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C4144

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SMILES string:
[Na+].[O-]C(=O)c1ccccc1.CN2C(=O)N(C)c3ncn(C)c3C2=O

InChI:
1S/C8H10N4O2.C7H6O2.Na/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2;8-7(9)6-4-2-1-3-5-6;/h4H,1-3H3;1-5H,(H,8,9);/q;;+1/p-1

InChI key:
JWBPVFVNISJVEM-UHFFFAOYSA-M

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antibiotic activity spectrum:
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SMILES string:
NC(=O)N1c2ccccc2C3OC3c4ccccc14

InChI:
1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)

InChI key:
ZRWWEEVEIOGMMT-UHFFFAOYSA-N