Description

• Thioflavin T is a cell-permeable fluorescent amyloid stain
• This cationic benzothiazole dye increases in fluorescence upon binding to the stacked β sheets of amyloid fibrils
• Thioflavin T is used to confirm formation of β sheet structure from mutant huntingtin exon-1 aggregates (Ex1Q48) in vitro
• Thioflavin T is also used to monitor the kinetics of in vitro polyglutamine amyloid formation of tNhtt-42Q aggregates in a Huntington's disease cell model
• Insoluble senile plaques of Aβ in brain tissues are commonly stained with Thioflavin T
• Excitation/emission maxima = 440/485 nm
• This product is supplied with a high degree of hydration and some residual inorganic salts, the amount of which are batch dependent
• Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.