76-371-0
Tocris Bioscience™ GSK 329
Manufacturer: Tocris Bioscience™
CAS Number: 1268490-12-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 76-371-0-Each-of-1 | In Stock | ₹ 30,982.99 |
76-371-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,982.99
GST (18%): ₹ 5,576.938
Total Price: ₹ 36,559.928
Chemical Name or Material
N-[3,5-Dichloro-4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-N'-[3-(trifluoromethyl)phenyl]urea
Quantity
10 mg
Molecular Formula
C19H14Cl2F3N5O2
CAS
1268490-12-5
Target
MAPK Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / GSK329 / 5mg / 713704408 / HY-117243 / / 1268490-12-5 / [null] / 472.250 / C19H14Cl2F3N5O2 | eMolecules | ₹ 30,226.64 | |
 | N-[3,5-Dichloro-4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-N′-[3-(trifluoromethyl)phenyl]urea | Aaron Chemicals LLC | ₹ 10,695.00 - ₹ 1,29,024.48 |
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Description
- Description GSK 329 is a potent and selective TNNI3K (cardiac troponin I-interacting kinase) inhibitor (IC50 = 10 nM)
- It exhibits selectivity for TNNI3K over human VEGFR2 (40-fold), p38α (80-fold), B-Raf (>200-fold) and displays >100-fold selectivity over 80% of 185 kinases tested
- In vivo , GSK 329 reduces infarct size, ROS levels, and p38 activation in a mouse model of ischemia/reperfusion cardiac injury
- This compound is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[3,5-Dichloro-4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-N'-[3-(trifluoromethyl)phenyl]urea
Quantity: 10 mg
Molecular Formula: C19H14Cl2F3N5O2
CAS: 1268490-12-5
Target: MAPK Inhibitors
Purity: 0.98
Chemical Name or Material:
N-[3,5-Dichloro-4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-N'-[3-(trifluoromethyl)phenyl]urea
Quantity:
10 mg
Molecular Formula:
C19H14Cl2F3N5O2
CAS:
1268490-12-5
Target:
MAPK Inhibitors
Purity:
0.98
Chemical Name or Material: __
Quantity: 100 μg
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100 μg
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300 μg
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