78-651-0
Tocris Bioscience™ AMG 900
Manufacturer: Fischer Scientific
CAS Number: 945595-80-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-651-0-Each-of-1 | In Stock | ₹ 16,384.74 |
78-651-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,384.74
GST (18%): ₹ 2,949.253
Total Price: ₹ 19,333.993
Chemical Name or Material
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity
10 mg
Molecular Formula
C28H21N7OS
CAS
945595-80-2
Target
Aurora Kinase Inhibitors
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ AMG 900 | Fischer Scientific | -- | |
| | Tocris Bioscience™ AMG 900 | Fischer Scientific | ₹ 69,089.70 | |
 | eMolecules AMG-900 | 945595-80-2 | MFCD18633194 | 10mg | eMolecules | ₹ 7,682.43 | |
 | Selleck Chemical LLC AMG-900 5mg 945595-80-2 | Selleck Chemical LLC | ₹ 17,454.24 | |
 | 945595-80-2 | AMG-900 | A2B Chem | ₹ 2,395.68 - ₹ 49,111.44 |
Related Products
Description
- AMG 900 is a potent pan-Aurora kinase inhibitor (IC50 values are 1 nM, 4 nM, and 5 nM for Aurora C, B, and A, respectively)
- It is more than 10-fold selective for Aurora kinases over JNK2, Tie2, p38α, Met, and TYK2
- AMG 900 inhibits autophosphorylation of Aurora A and B, as well as the phosphorylation of histone H3 on Ser in HeLa cells
- AMG 900 inhibits proliferation of 26 tumor cell lines (EC50 ranges from 0.7 nM - 5.3 nM), including Paclitaxel (Cat
- No
- 1097)-resistant tumor cell lines
- In an HCT116 tumor xenograft model, AMG 900 inhibits phosphorylation of histone H3 and tumor growth
- It is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity: 10 mg
Molecular Formula: C28H21N7OS
CAS: 945595-80-2
Target: Aurora Kinase Inhibitors
Purity: 98%
Chemical Name or Material:
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity:
10 mg
Molecular Formula:
C28H21N7OS
CAS:
945595-80-2
Target:
Aurora Kinase Inhibitors
Purity:
98%
Chemical Name or Material: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity: 50 mg
Molecular Formula: C28H21N7OS
CAS: 945595-80-2
Target: Aurora Kinase Inhibitors
Purity: 98%
Chemical Name or Material:
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity:
50 mg
Molecular Formula:
C28H21N7OS
CAS:
945595-80-2
Target:
Aurora Kinase Inhibitors
Purity:
98%
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: __
CAS: 1224095-25-3
Target: __
Purity: 0.95
Chemical Name or Material:
__
Quantity:
1 mg
Molecular Formula:
__
CAS:
1224095-25-3
Target:
__
Purity:
0.95
Chemical Name or Material: (2S,4R)-1-((S)-2-(6-Azidohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity: 25 mg
Molecular Formula: C28H39N7O4S
CAS: 2821804-11-7
Target: Degrader Building Blocks
Purity: 0.95
Chemical Name or Material:
(2S,4R)-1-((S)-2-(6-Azidohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity:
25 mg
Molecular Formula:
C28H39N7O4S
CAS:
2821804-11-7
Target:
Degrader Building Blocks
Purity:
0.95