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7146026

Tocris Bioscience™ TL4-12

Potent MAP4K2 (GCK) inhibitor

Manufacturer: Fischer Scientific

CAS Number: 1620820-12-3

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Chemical Name or Material

4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide

CAS

1620820-12-3

Molecular Formula

C25H27F3N6O2

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
59-101-0
Tocris Bioscience™ TL4-12
Fischer Scientific ₹ 24,613.90
59-105-0
Tocris Bioscience™ TL4-12
Fischer Scientific ₹ 1,02,624.09
AX63050
1620820-12-3 | 4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide
A2B Chem ₹ 4,791.36 - ₹ 60,490.92

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Description

  • Potent MAP4K2 (GCK) inhibitor (IC50 = 37 nM)
  • Exhibits >70-fold selectivity for MAP4K2 over TAK1 (IC50 = 2.7 μM for TAK1)
  • Inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation, in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide
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1620820-12-3
Molecular Formula:
C25H27F3N6O2
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