54-295-R

Tocris Bioscience™ NG 25

Manufacturer: Tocris Bioscience™

CAS Number: 1315355-93-1

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Pack Size SKU Availability Price
Each of 1 54-295-R-Each-of-1 In Stock ₹ 40,897.68

54-295-R - Each of 1

₹ 40,897.68

In Stock

Quantity

1

Base Price: ₹ 40,897.68

GST (18%): ₹ 7,361.582

Total Price: ₹ 48,259.262

Chemical Name or Material

N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

Quantity

5 mg

Molecular Formula

C29H30F3N5O2

Purity

>98%

CAS

1315355-93-1

Target

Other Kinase Inhibitors

Formula Weight

537.58

Other Options

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Description

  • NG 25 is a TGF-β-activated kinase (TAK1) inhibitor (IC50 = 149 nM)
  • Also inhibits LYN, MAP4K2 and Abl kinase activity (IC50 values are 12.9, 21.7 and 75.2 nM, respectively)
  • Suppresses CpG A and CpG B-stimulated secretion of IFN-α and TLR7/8 agonist CL097-stimulated secretion of IFN-β in Gen 2.2 leukemia cells in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

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5 mg

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C29H30F3N5O2

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>98%

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1315355-93-1

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