77-155-0
Tocris Bioscience™ C25-140
Manufacturer: Fischer Scientific
CAS Number: 1358099-18-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 77-155-0-Each-of-1 | In Stock | ₹ 1,25,757.00 |
77-155-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,25,757.00
GST (18%): ₹ 22,636.26
Total Price: ₹ 1,48,393.26
Chemical Name or Material
3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone
Quantity
50 mg
Molecular Formula
C26H31N7O
CAS
1358099-18-9
Target
Ubiquitin Ligase (E3) Inhibitors
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ C25-140 | Fischer Scientific | -- | |
 | Tocris Bioscience™ C25-140 | Fischer Scientific | ₹ 29,948.50 | |
 | Selleck Chemical LLC C25-140 5mg 1358099-18-9 | Selleck Chemical LLC | ₹ 19,971.60 | |
 | Medchemexpress LLC HY-120934 5mg Medchemexpress, C25-140 CAS:1358099-18-9 Purity:>98% | Medchemexpress LLC | ₹ 16,821.00 | |
| | eMolecules Medchem Express / C25-140 / 5mg / 455326192 / HY-120934 / / 1358099-18-9 / MFCD27163630 / 457.582 / C26H31N7O | eMolecules | ₹ 23,581.44 | |
 | 1358099-18-9 | C25-140 | A2B Chem | ₹ 3,204.00 - ₹ 48,327.00 |
Related Products
Description
- C25-140 binds directly to TNF receptor-associated factor 6 (TRAF6) and inhibits its interaction with ubiquitin-conjugating enzyme Ubc13
- C25-140 reduces TRAF6-Ubc13 activity and decreases NF-κB activation and inflammatory signaling in vitro
- C25-140 exhibits selectivity for TRAF6 over other E3 ligases except cIAP1
- In in vivo mouse models of autoimmune psoriasis and rheumatoid arthritis, the compound improves disease symptoms
- The compound also suppresses the pro-inflammatory signaling activity of IL-17A and prevents its inhibitory effect on the anti-HBV action of IFN-α HepG2 cells.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Compare Similar Items
Show Difference
Chemical Name or Material: 3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone
Quantity: 50 mg
Molecular Formula: C26H31N7O
CAS: 1358099-18-9
Target: Ubiquitin Ligase (E3) Inhibitors
Chemical Name or Material:
3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone
Quantity:
50 mg
Molecular Formula:
C26H31N7O
CAS:
1358099-18-9
Target:
Ubiquitin Ligase (E3) Inhibitors
Chemical Name or Material: 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Quantity: 50 mg
Molecular Formula: C14H13N3O4
CAS: 1352827-50-9
Target: Active Degrader Negative Controls
Chemical Name or Material:
4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Quantity:
50 mg
Molecular Formula:
C14H13N3O4
CAS:
1352827-50-9
Target:
Active Degrader Negative Controls
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: __
CAS: 272105-42-7
Target: __
Chemical Name or Material:
__
Quantity:
1 mg
Molecular Formula:
__
CAS:
272105-42-7
Target:
__
Chemical Name or Material: N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide
Quantity: 10 mg
Molecular Formula: C20H14F3N3O7S
CAS: 2765625-93-0
Target: Molecular Glues
Chemical Name or Material:
N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide
Quantity:
10 mg
Molecular Formula:
C20H14F3N3O7S
CAS:
2765625-93-0
Target:
Molecular Glues