7180126

Tocris™ BAY 87-2243

Mitochondrial complex I inhibitor

Manufacturer: Fischer Scientific

CAS Number: 1227158-85-1

The price for this product is unavailable. Please request a quote

Chemical Name or Material

1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine

CAS

1227158-85-1

Molecular Formula

C26H26F3N7O2

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
69-805-TOC
Tocris™ BAY 87-2243
Fischer Scientific ₹ 8,641.56
69-802-5
Tocris™ BAY 87-2243
Fischer Scientific --
50-226-0178
Medchemexpress LLC HY-15836 10mg , BAY 87-2243 CAS:1227158-85-1 Purity:>98%
Medchemexpress LLC ₹ 12,128.13
50-190-5205
Apexbio Technology LLC BAY 87-2243, 50mg. Cas: 1227158-85-1 MFCD: MFCD28143915. HIF-1 inhibitor,potent and selective
Apexbio Technology LLC ₹ 44,747.88
50-136-4625
Selleck Chemical LLC BAY 87-2243 10mg 1227158-85-1
Selleck Chemical LLC ₹ 18,172.94
NC1633754
eMolecules​ BAY 87-2243 | 1227158-85-1 | MFCD28143915 | 50mg
eMolecules​ ₹ 71,142.28

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Description

  • Exhibits no effect on mitochondrial complex III Induces mitochondrial permeability transition pore (mPTP) opening, stimulates autophagosome formation and mitophagy, and increases ROS levels Activates necroptotic and ferroptotic cell death Also inhibits hypoxia-induced gene activation Induces cell death in melanoma cell lines in vitro and exhibits antitumor activity in a mouse NSCLC xenograft model in vivo

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine

CAS:
1227158-85-1

Molecular Formula:
C26H26F3N7O2

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Molecular Formula:
C24H28N4O4S.C2HF3O2

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