7180128
Tocris™ JTP 103237
Potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1883864-16-1
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Chemical Name or Material
7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine
CAS
1883864-16-1
Molecular Formula
C24H29F3N6O
Purity
98%
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| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ JTP 103237 | Fischer Scientific | -- | |
| | Tocris™ JTP 103237 | Fischer Scientific | -- |
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Description
- Potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor (IC50 = 20 - 40 nM) Displays >7000-fold selectivity for human MOGAT2 over human DGAT2
- Modulates intestinal lipid absorption in mice Decreases triglyceride, diacylglycerol and fatty acid synthesis in mouse model of fatty liver Chronic treatment decreases hepatic triglyceride content and body weight, and improves glucose tolerance in diet-induced obese mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine
CAS: 1883864-16-1
Molecular Formula: C24H29F3N6O
Purity: 98%
Chemical Name or Material:
7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine
CAS:
1883864-16-1
Molecular Formula:
C24H29F3N6O
Purity:
98%
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Chemical Name or Material: 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
CAS: 886047-13-8
Molecular Formula: C13H14ClN3O2S
Purity: 98%
Chemical Name or Material:
3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
CAS:
886047-13-8
Molecular Formula:
C13H14ClN3O2S
Purity:
98%