7161660

Tocris Bioscience™ Pexacerfont

Potent and selective CRF1 antagonist; anxiolytic

Manufacturer: Fischer Scientific

CAS Number: 459856-18-9

The price for this product is unavailable. Please request a quote

Chemical Name or Material

8-(6-Methoxy-2-methyl-3-pyridinyl)-2,7-dimethyl-N-[(1R)-1-methylpropyl]pyrazolo[1,5-a]-1,3,5-triazin-4-amine

Molecular Formula

C18H24N6O

Purity

98%

CAS

459856-18-9

Formula Weight

340.43

Related Products

Img

Fischer Scientific

7180128

Potent and selective monoacyglycero...

Img

Fischer Scientific

7161665

High affinity CRF1 antagonist; oral...

Img

Thermo Scientific™

AC467951000

--

Img

Fischer Scientific

7139262

Potent and selective USP1-UAF1 allo...

Img

Fischer Scientific

7116091

Potent and selective PDE8B/8A inhib...

Img

Fischer Scientific

7250113

Potent and selective ErbB2 inhibito...

Img

Fischer Scientific

7180142

Positive allosteric modulators of m...

Img

Fischer Scientific

76-401-0

--

Description

  • Potent and selective corticotropin-releasing factor 1 receptor (CRF1) antagonist (IC50 = 6.1 nM) Displays >150 fold selectivity for CRF1 over CRF2b Inhibits CRF-mediated adrenocorticotropic hormone (ACTH) release from pituitary cell culture (IC50 = 129 nM) Displays anxiolytic effects in rat behavioral paradigms

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

7161660

Potent and selective CRF1 antagonis...


Chemical Name or Material:
8-(6-Methoxy-2-methyl-3-pyridinyl)-2,7-dimethyl-N-[(1R)-1-methylpropyl]pyrazolo[1,5-a]-1,3,5-triazin-4-amine

Molecular Formula:
C18H24N6O

Purity:
98%

CAS:
459856-18-9

Formula Weight:
340.43

Img

Fischer Scientific

7161661

Negative allosteric modulator of 3-...


Chemical Name or Material:
2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide

Molecular Formula:
C14H11N3O6

Purity:
98%

CAS:
304481-72-9

Formula Weight:
317.25

Img

Fischer Scientific

7161662

Negative allosteric modulator of 3-...


Chemical Name or Material:
2-Chloro-4-[5-[[2-[(ethylamino)thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid

Molecular Formula:
C15H14ClN3O3S

Purity:
98%

CAS:
592474-91-4

Formula Weight:
351.81

Img

Fischer Scientific

7161664

PSAML141F-GlyR and PSAML141F,Y115F-...


Chemical Name or Material:
N-(3 S)-1-Azabicyclo[2.2.2 ]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate

Molecular Formula:
C16H22N2O3.CF3CO2H

Purity:
98%

CAS:
1336913-03-1

Formula Weight:
404.38