7180142
Tocris™ VU 6005649
Positive allosteric modulators of mGlu7 and mGlu8 receptors. Also NK1 antagonist.
Manufacturer: Fischer Scientific
CAS Number: 2137047-43-7
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Chemical Name or Material
3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS
2137047-43-7
Molecular Formula
C16H12F5N3O
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ VU 6005649 | Fischer Scientific | ₹ 19,550.46 | |
| | Tocris™ VU 6005649 | Fischer Scientific | ₹ 82,308.72 | |
 | eMolecules Medchem Express / VU6005649 / 5mg / 446259212 / HY-107982 / / 2137047-43-7 / [null] / 357.284 / C16H12F5N3O | eMolecules | ₹ 8,816.10 | |
 | 2137047-43-7 | VU6005649 | A2B Chem | ₹ 17,283.12 - ₹ 87,185.64 |
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Description
- Positive allosteric modulator of mGlu7 and mGlu8 receptors (EC50 = 0.65 μM and 2.6 μM for mGlu7 and mGlu8, respectively) Displays >3.8 fold selectivity for mGlu7 and mGlu8 over other mGlu receptors (EC50 >10 μM for mGlu1,2,3,4,5,6) Also NK1 receptor antagonist (Ki= 650 nM, IC50 = 3.4 μM) Brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS: 2137047-43-7
Molecular Formula: C16H12F5N3O
Purity: 98%
Chemical Name or Material:
3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS:
2137047-43-7
Molecular Formula:
C16H12F5N3O
Purity:
98%
Chemical Name or Material: 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide
CAS: 873080-25-2
Molecular Formula: C19H17Cl2N3O4S
Purity: 98%
Chemical Name or Material:
5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide
CAS:
873080-25-2
Molecular Formula:
C19H17Cl2N3O4S
Purity:
98%
Chemical Name or Material: 3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]benzamide
CAS: 1826865-46-6
Molecular Formula: C36H48N6O3
Purity: 98%
Chemical Name or Material:
3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]benzamide
CAS:
1826865-46-6
Molecular Formula:
C36H48N6O3
Purity:
98%
Chemical Name or Material: N-[(2,4-Difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1'-biphenyl]-2-carboxamide
CAS: 498577-46-1
Molecular Formula: C30H26F2N2O3
Purity: 98%
Chemical Name or Material:
N-[(2,4-Difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1'-biphenyl]-2-carboxamide
CAS:
498577-46-1
Molecular Formula:
C30H26F2N2O3
Purity:
98%