76-401-0

Tocris Bioscience™ Tucatinib

Manufacturer: Fischer Scientific

CAS Number: 937263-43-9

Select a Size

Pack Size SKU Availability Price
Each of 1 76-401-0-Each-of-1 In Stock ₹ 18,181.50

76-401-0 - Each of 1

₹ 18,181.50

In Stock

Quantity

1

Base Price: ₹ 18,181.50

GST (18%): ₹ 3,272.67

Total Price: ₹ 21,454.17

Chemical Name or Material

N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine

Quantity

10 mg

Molecular Formula

C26H24N8O2

CAS

937263-43-9

Target

EGF Receptor Inhibitors

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250113
Tocris Bioscience™ Tucatinib
Fischer Scientific --
76-405-0
Tocris Bioscience™ Tucatinib
Fischer Scientific ₹ 76,276.74
50-136-6438
Selleck Chemical LLC Tucatinib (Irbinitinib, ONT-380) 25mg 937263-43-9 ARRY-380
Selleck Chemical LLC ₹ 28,440.14
50-244-4147
eMolecules​ Ambeed / N4-(4-([124]Triazolo[15-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(44-dimethyl-45-dihydrooxazol-2-yl)quinazoline-46-diamine / 100mg / 524984446 / A100992 / / 937263-43-9 / MFCD22380467 / 480.532 / C26H24N8O2
eMolecules​ ₹ 9,949.77
50-202-9187
Medchemexpress LLC HY-16069 50mg Medchemexpress, Tucatinib CAS:937263-43-9 Purity:>98%
Medchemexpress LLC ₹ 22,459.50

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Description

  • Tucatinib is a potent and selective ErbB-2 (also called HER2) kinase inhibitor (IC50 = 7 nM)
  • It exhibits >50-fold selectivity for ErbB-2 over EGFR
  • In vitro , Tucatinib inhibits ErbB-2 signaling activity and cell proliferation in ErbB-2-amplified breast cancer cell lines (BT-474)
  • In vivo , Tucatinib (25-100 mg/kg) reduces tumor volume in breast and gastric xenograft mouse models.This compound is orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

76-401-0

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Chemical Name or Material:
N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine

Quantity:
10 mg

Molecular Formula:
C26H24N8O2

CAS:
937263-43-9

Target:
EGF Receptor Inhibitors

Purity:
0.98

Img

Fischer Scientific

76-405-0

--


Chemical Name or Material:
N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine

Quantity:
50 mg

Molecular Formula:
C26H24N8O2

CAS:
937263-43-9

Target:
EGF Receptor Inhibitors

Purity:
0.98

Img

Tocris Bioscience™

76-442

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Chemical Name or Material:
(S)-1-(Methylsulfonyl)-N-[4-(methylthio)-1-oxo-1-[[4-[3-(pyridin-4-yl)phenyl]thiazol-2-yl]amino]butan-2-yl]-1H-pyrrole-3-carboxamide

Quantity:
2 mg

Molecular Formula:
C25H25N5O4S3

CAS:
2368903-18-6

Target:
Bromodomain Inhibitors

Purity:
0.95

Img

Invitrogen™

76-455-1KT

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Chemical Name or Material:
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Quantity:
1 kit

Molecular Formula:
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CAS:
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Target:
__

Purity:
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