78-641-0
Tocris Bioscience™ LY 2109761
Manufacturer: Fischer Scientific
CAS Number: 700874-71-1
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-641-0-Each-of-1 | In Stock | ₹ 13,234.30 |
78-641-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,234.30
GST (18%): ₹ 2,382.174
Total Price: ₹ 15,616.474
Chemical Name or Material
4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
Quantity
10 mg
Molecular Formula
C26H27N5O2
CAS
700874-71-1
Target
TGF-beta Receptor Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ LY 2109761 | Fischer Scientific | -- | |
| | Tocris Bioscience™ LY 2109761 | Fischer Scientific | ₹ 55,714.00 |
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Description
- LY 2109761 is a selective dual TGF-β receptor type I and II (TβRI/II) inhibitor (Ki values are 38 and 300 nM in a cell-free assay, respectively); it inhibits the kinase activity of both TGF-βRI and TGF-βRII
- In vitro , it significantly inhibits the growth, motility, and invasiveness of L3.6pl/GLT pancreatic cancer cells and completely suppresses TGF-β-induced Smad2 phosphorylation
- In vivo , LY 2109761, in combination with Gemcitabine, significantly reduces tumor volume and spontaneous abdominal metastases in a murine model of metastatic pancreatic cancer
- LY 2109761 is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
Quantity: 10 mg
Molecular Formula: C26H27N5O2
CAS: 700874-71-1
Target: TGF-beta Receptor Inhibitors
Purity: 0.98
Chemical Name or Material:
4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
Quantity:
10 mg
Molecular Formula:
C26H27N5O2
CAS:
700874-71-1
Target:
TGF-beta Receptor Inhibitors
Purity:
0.98
Chemical Name or Material: 4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
Quantity: 50 mg
Molecular Formula: C26H27N5O2
CAS: 700874-71-1
Target: TGF-beta Receptor Inhibitors
Purity: 0.98
Chemical Name or Material:
4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
Quantity:
50 mg
Molecular Formula:
C26H27N5O2
CAS:
700874-71-1
Target:
TGF-beta Receptor Inhibitors
Purity:
0.98
Chemical Name or Material: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity: 10 mg
Molecular Formula: C28H21N7OS
CAS: 945595-80-2
Target: Aurora Kinase Inhibitors
Purity: 98%
Chemical Name or Material:
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity:
10 mg
Molecular Formula:
C28H21N7OS
CAS:
945595-80-2
Target:
Aurora Kinase Inhibitors
Purity:
98%
Chemical Name or Material: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity: 50 mg
Molecular Formula: C28H21N7OS
CAS: 945595-80-2
Target: Aurora Kinase Inhibitors
Purity: 98%
Chemical Name or Material:
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Quantity:
50 mg
Molecular Formula:
C28H21N7OS
CAS:
945595-80-2
Target:
Aurora Kinase Inhibitors
Purity:
98%