7110956
Tocris Bioscience™ DMH2
Type I BMP receptor inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1206711-14-9
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Chemical Name or Material
4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Target
BMP and Other Activin Receptor Inhibitors
Formula Weight
451.52
CAS
1206711-14-9
Molecular Formula
C27H25N5O2
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ DMH2 | Fischer Scientific | ₹ 1,11,912.48 | |
| | Tocris Bioscience™ DMH2 | Fischer Scientific | ₹ 26,780.28 | |
 | Sigma Aldrich Fine Chemicals Biosciences DMH2 >=98% (HPLC) | 1206711-14-9 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 14,463.92 | |
 | 1206711-14-9 | DMH2 | A2B Chem | ₹ 36,876.36 |
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Description
- Type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively)
- Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2
- Also binds to TGFBR2 (Ki = 85 nM)
- Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro
- Enhances liver regeneration in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Target: BMP and Other Activin Receptor Inhibitors
Formula Weight: 451.52
CAS: 1206711-14-9
Molecular Formula: C27H25N5O2
Purity: >98%
Chemical Name or Material:
4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Target:
BMP and Other Activin Receptor Inhibitors
Formula Weight:
451.52
CAS:
1206711-14-9
Molecular Formula:
C27H25N5O2
Purity:
>98%
Chemical Name or Material: 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide
Target: Formyl Peptide Receptor Agonists
Formula Weight: 445.51
CAS: 786706-21-6
Molecular Formula: C26H27N3O4
Purity: >98%
Chemical Name or Material:
4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide
Target:
Formyl Peptide Receptor Agonists
Formula Weight:
445.51
CAS:
786706-21-6
Molecular Formula:
C26H27N3O4
Purity:
>98%
Chemical Name or Material: N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
Target: Synthetic Cathepsin Inhibitors
Formula Weight: 411.54
CAS: 354813-19-7
Molecular Formula: C23H33N5O2
Purity: >98%
Chemical Name or Material:
N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
Target:
Synthetic Cathepsin Inhibitors
Formula Weight:
411.54
CAS:
354813-19-7
Molecular Formula:
C23H33N5O2
Purity:
>98%
Chemical Name or Material: 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine
Target: Other Calcium Channel Activators
Formula Weight: 355.27
CAS: 448947-81-7
Molecular Formula: C13H8Cl2N4S2
Purity: >99%
Chemical Name or Material:
2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine
Target:
Other Calcium Channel Activators
Formula Weight:
355.27
CAS:
448947-81-7
Molecular Formula:
C13H8Cl2N4S2
Purity:
>99%