7250113
Tocris Bioscience™ Tucatinib
Potent and selective ErbB2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 937263-43-9
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Chemical Name or Material
N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine
Target
EGF Receptor Inhibitors
Purity
0.98
CAS
937263-43-9
Molecular Formula
C26H24N8O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Tucatinib | Fischer Scientific | ₹ 18,181.50 | |
| | Tocris Bioscience™ Tucatinib | Fischer Scientific | ₹ 76,276.74 | |
 | Selleck Chemical LLC Tucatinib (Irbinitinib, ONT-380) 25mg 937263-43-9 ARRY-380 | Selleck Chemical LLC | ₹ 28,440.14 | |
 | eMolecules Ambeed / N4-(4-([124]Triazolo[15-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(44-dimethyl-45-dihydrooxazol-2-yl)quinazoline-46-diamine / 100mg / 524984446 / A100992 / / 937263-43-9 / MFCD22380467 / 480.532 / C26H24N8O2 | eMolecules | ₹ 9,949.77 | |
 | Medchemexpress LLC HY-16069 50mg Medchemexpress, Tucatinib CAS:937263-43-9 Purity:>98% | Medchemexpress LLC | ₹ 22,459.50 |
Related Products
Description
- Tucatinib is a potent and selective ErbB-2 (also called HER2) kinase inhibitor (IC50 = 7 nM)
- It exhibits >50-fold selectivity for ErbB-2 over EGFR
- In vitro , Tucatinib inhibits ErbB-2 signaling activity and cell proliferation in ErbB-2-amplified breast cancer cell lines (BT-474)
- In vivo , Tucatinib (25-100 mg/kg) reduces tumor volume in breast and gastric xenograft mouse models.This compound is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine
Target: EGF Receptor Inhibitors
Purity: 0.98
CAS: 937263-43-9
Molecular Formula: C26H24N8O2
Chemical Name or Material:
N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4 ]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine
Target:
EGF Receptor Inhibitors
Purity:
0.98
CAS:
937263-43-9
Molecular Formula:
C26H24N8O2
Chemical Name or Material: N-[[(1 R,2 R)-2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
Target: Melatonin (MT) Receptor Agonists
Purity: 0.98
CAS: 609799-22-6
Molecular Formula: C15H19NO2
Chemical Name or Material:
N-[[(1 R,2 R)-2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
Target:
Melatonin (MT) Receptor Agonists
Purity:
0.98
CAS:
609799-22-6
Molecular Formula:
C15H19NO2
Chemical Name or Material: 8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target: Proteasome Inhibitors
Purity: 0.98
CAS: 2084868-04-0
Molecular Formula: C30H24N6O2S4
Chemical Name or Material:
8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target:
Proteasome Inhibitors
Purity:
0.98
CAS:
2084868-04-0
Molecular Formula:
C30H24N6O2S4
Chemical Name or Material: 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Target: PPAR gamma/NR1C3
Purity: 0.98
CAS: 315224-26-1
Molecular Formula: C21H12Cl4N2O3S
Chemical Name or Material:
2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Target:
PPAR gamma/NR1C3
Purity:
0.98
CAS:
315224-26-1
Molecular Formula:
C21H12Cl4N2O3S