81-221-0

Tocris Bioscience™ MR 24

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 81-221-0-Each-of-1 In Stock ₹ 14,079.75

81-221-0 - Each of 1

₹ 14,079.75

In Stock

Quantity

1

Base Price: ₹ 14,079.75

GST (18%): ₹ 2,534.355

Total Price: ₹ 16,614.105

Chemical Name or Material

8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride

Target

Other Kinase Inhibitors

Purity

0.98

Quantity

10 mg

Molecular Formula

C26H29ClN6O3.3HCl

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Description

  • MR 24 is a potent and selective MST3 kinase binding inhibitor with >10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively)
  • MR 24 increases the number of cells in G1 phase of cell cycle, is non-cytotoxic and cell permeable
  • Shows 90% stability over 1 hour in activated liver microsomes in vivo .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

81-221-0

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Chemical Name or Material:
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride

Target:
Other Kinase Inhibitors

Purity:
0.98

Quantity:
10 mg

Molecular Formula:
C26H29ClN6O3.3HCl

Img

Fischer Scientific

81-225-0

--


Chemical Name or Material:
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride

Target:
Other Kinase Inhibitors

Purity:
0.98

Quantity:
50 mg

Molecular Formula:
C26H29ClN6O3.3HCl

Img

Tocris Bioscience™

81-342-00U

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Chemical Name or Material:
4-((4-(1,2,4,5-Tetrazin-3-yl)benzyl)carbamoyl)-2-(3-(3-fluoroazetidin-1-ium-1-ylidene)-7-(3-fluoroazetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate

Target:
Fluorescent Dyes

Purity:
0.9

Quantity:
200 μg

Molecular Formula:
C38H33F2N7O3Si

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SPEX CertiPrep

81-41B-1000

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Chemical Name or Material:
8141 Mix-B

Target:
__

Purity:
__

Quantity:
1 mL

Molecular Formula:
__