7116094
G 5555
High affinity group 1 PAK inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1648863-90-4
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Chemical Name or Material
8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range
>98%
Formula Weight
Observed MW: 492.96
CAS
1648863-90-4
Molecular Formula
C25H25ClN6O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | G 5555 | Fischer Scientific | ₹ 21,680.40 | |
| | G 5555 | Fischer Scientific | ₹ 90,954.44 | |
 | Medchemexpress LLC HY-19635 10mg , G-5555 CAS:1648863-90-4 Purity:>98% | Medchemexpress LLC | ₹ 14,952.00 | |
 | eMolecules Medchem Express / G-5555 / 1mg / 446270042 / HY-19635 / / 1648863-90-4 / MFCD28506227 / 492.960 / C25H25ClN6O3 | eMolecules | ₹ 9,170.56 | |
 | 1648863-90-4 | G-5555 | A2B Chem | ₹ 9,968.00 - ₹ 1,41,955.00 |
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Description
- High affinity group 1 PAK (pan-PAK1, 2 and 3) inhibitor (Ki = 3.7 nM; pMEK IC50 = 69 nM)
- Of 235 kinases tested, other than PAK1, eight (PAK2, PAK3, KHS1, Lck, MST3, MST4, SIK2, and YSK1) were inhibited >70%
- Exhibits low hERG channel activity (<50% inhibition at 10 μM)
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range: >98%
Formula Weight: Observed MW: 492.96
CAS: 1648863-90-4
Molecular Formula: C25H25ClN6O3
Chemical Name or Material:
8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 492.96
CAS:
1648863-90-4
Molecular Formula:
C25H25ClN6O3
Chemical Name or Material: 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 364.44
CAS: 1933533-18-6
Molecular Formula: C22H24N2O3
Chemical Name or Material:
4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 364.44
CAS:
1933533-18-6
Molecular Formula:
C22H24N2O3
Chemical Name or Material: 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
Assay Percent Range: >98%
Formula Weight: Observed MW: 296.39
CAS: 1234569-09-5
Molecular Formula: C13H20N4O2S
Chemical Name or Material:
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 296.39
CAS:
1234569-09-5
Molecular Formula:
C13H20N4O2S
Chemical Name or Material: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Assay Percent Range: >98%
Formula Weight: Observed MW: 440.88
CAS: 1219810-16-8
Molecular Formula: C23H21ClN2O5
Chemical Name or Material:
(1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 440.88
CAS:
1219810-16-8
Molecular Formula:
C23H21ClN2O5