7116081
BAY 678
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 675103-36-3
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Chemical Name or Material
5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Assay Percent Range
>98%
Formula Weight
Observed MW: 400.35
CAS
675103-36-3
Molecular Formula
C20H15F3N4O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | BAY 678 | Fischer Scientific | ₹ 37,518.06 | |
| | BAY 678 | Fischer Scientific | ₹ 9,420.16 | |
 | Sigma Aldrich Fine Chemicals Biosciences BAY-678 >=98% (HPLC) | 675103-36-3 | MFCD29924806 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,634.45 | |
 | BAY-678 | Sigma Aldrich | ₹ 10,356.30 - ₹ 41,625.00 | |
 | 675103-36-3 | BAY678 | A2B Chem | ₹ 2,994.60 - ₹ 7,187.04 |
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Description
- Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM)
- Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases
- Effective in an acute lung injury model in vivo
- Orally bioavailable
- Inactive S-enantiomer (Cat.No.6389) also available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Assay Percent Range: >98%
Formula Weight: Observed MW: 400.35
CAS: 675103-36-3
Molecular Formula: C20H15F3N4O2
Chemical Name or Material:
5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 400.35
CAS:
675103-36-3
Molecular Formula:
C20H15F3N4O2
Chemical Name or Material: 7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
Assay Percent Range: >99%
Formula Weight: Observed MW: 415.45
CAS: 315698-17-0
Molecular Formula: C23H24F3N3O
Chemical Name or Material:
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 415.45
CAS:
315698-17-0
Molecular Formula:
C23H24F3N3O
Chemical Name or Material: N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride
Assay Percent Range: >98%
Formula Weight: Observed MW: 507.5
CAS: __
Molecular Formula: C25H34N6O.2HCl
Chemical Name or Material:
N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 507.5
CAS:
__
Molecular Formula:
C25H34N6O.2HCl
Chemical Name or Material: N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide
Assay Percent Range: >98%
Formula Weight: Observed MW: 539.64
CAS: 447459-51-0
Molecular Formula: C23H25NO8S3
Chemical Name or Material:
N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 539.64
CAS:
447459-51-0
Molecular Formula:
C23H25NO8S3