43-222

Tocris Bioscience™ JH 295

Manufacturer: Tocris Bioscience™

CAS Number: 1311143-71-1

Select a Size

Pack Size SKU Availability Price
Each of 1 43-222-Each-of-1 In Stock ₹ 50,617.30

43-222 - Each of 1

₹ 50,617.30

In Stock

Quantity

1

Base Price: ₹ 50,617.30

GST (18%): ₹ 9,111.114

Total Price: ₹ 59,728.414

Chemical Name or Material

N-[(3Z)-3-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methylene]-2,3-dihydro-2-oxo-1H-indol-5-yl]-2-propynamide

Assay Percent Range

>98%

Molecular Formula

C18H16N4O2

CAS

1311143-71-1

Quantity

2 mg

Formula Weight

Observed MW: 320.35

Other Options

Image Product Name Manufacturer Price Range
AE60928
1311143-71-1 | JH295
A2B Chem --

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Description

  • JH 295 is an irreversible Nek2 inhibitor (IC50=770 nM)
  • Inhibits Nek2 via alkylation of residue Cys22
  • Displays 5-fold selectivity for Nek2 over Cdk1
  • Exhibits no significant effect on Aurora B or Plk1 kinases, bipolar spindle assembly or spindle assembly checkpoint
  • Cell permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
N-[(3Z)-3-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methylene]-2,3-dihydro-2-oxo-1H-indol-5-yl]-2-propynamide

Assay Percent Range:
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Molecular Formula:
C18H16N4O2

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