7114670
Tocris Bioscience™ JH-II-127
Potent and selective LRRK2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1700693-08-8
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Chemical Name or Material
[4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Assay Percent Range
>98%
Formula Weight
Observed MW: 416.87
CAS
1700693-08-8
Molecular Formula
C19H21ClN6O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ JH-II-127 | Fischer Scientific | ₹ 25,606.40 | |
| | Tocris Bioscience™ JH-II-127 | Fischer Scientific | ₹ 1,07,388.07 | |
 | Medchemexpress LLC HY-16936 5mg Medchemexpress, JH-II-127 CAS:1700693-08-8 Purity:>98% | Medchemexpress LLC | ₹ 11,678.94 | |
 | JH-II-127 | ChemScene | ₹ 8,556.00 - ₹ 54,416.16 |
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Description
- Potent and selective LRRK2 inhibitor (IC50 values are 2.2, 6.6 and 47.7 nM for G2019S-mutant, wild-type and A2016T-mutant LRRK2, respectively)
- Selective for LRRK2 over a panel of 138 kinases
- Brain penetrant and orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Assay Percent Range: >98%
Formula Weight: Observed MW: 416.87
CAS: 1700693-08-8
Molecular Formula: C19H21ClN6O3
Chemical Name or Material:
[4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 416.87
CAS:
1700693-08-8
Molecular Formula:
C19H21ClN6O3
Chemical Name or Material: 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Assay Percent Range: >98%
Formula Weight: Observed MW: 273.24
CAS: 19171-19-8
Molecular Formula: C13H11N3O4
Chemical Name or Material:
4-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 273.24
CAS:
19171-19-8
Molecular Formula:
C13H11N3O4
Chemical Name or Material: 6-[[(2 S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1 H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 396.36
CAS: 1215197-37-7
Molecular Formula: C18H19F3N4O3
Chemical Name or Material:
6-[[(2 S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1 H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 396.36
CAS:
1215197-37-7
Molecular Formula:
C18H19F3N4O3
Chemical Name or Material: 6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium
Assay Percent Range: >99%
Formula Weight: Observed MW: 397.35
CAS: 96201-88-6
Molecular Formula: C23H14F2NO2Na
Chemical Name or Material:
6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 397.35
CAS:
96201-88-6
Molecular Formula:
C23H14F2NO2Na