73-715-0
Tocris Bioscience™ Neratinib
Manufacturer: Fischer Scientific
CAS Number: 698387-09-6
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 73-715-0-Each-of-1 | In Stock | ₹ 73,444.70 |
73-715-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 73,444.70
GST (18%): ₹ 13,220.046
Total Price: ₹ 86,664.746
Chemical Name or Material
(2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Quantity
50 mg
Molecular Formula
C30H29ClN6O3
CAS
698387-09-6
Target
EGF Receptor Inhibitors
Purity
0.98
Other Options
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Description
- Neratinib is a potent, irreversible inhibitor of HER-2/ErbB2 receptor tyrosine kinase and EGFR kinase (IC50 = 59 nM and 92 nM, respectively)
- Neratinib reduces receptor autophosphorylation and proliferation of EGFR-dependent cancer cells, blocks cell-cycle progression and inhibits HER-2 signaling pathways
- Neratinib suppresses proliferation of gefitinib -resistant non-small cell lung cancer cells expressing mutant EGFR
- Also inhibits MST1 (IC50 = 37.7 nM)
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: (2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Quantity: 50 mg
Molecular Formula: C30H29ClN6O3
CAS: 698387-09-6
Target: EGF Receptor Inhibitors
Purity: 0.98
Chemical Name or Material:
(2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Quantity:
50 mg
Molecular Formula:
C30H29ClN6O3
CAS:
698387-09-6
Target:
EGF Receptor Inhibitors
Purity:
0.98
Chemical Name or Material: N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Quantity: 10 mg
Molecular Formula: C14H15N5
CAS: 923596-52-5
Target: Cyclin-dependent Kinase Inhibitors
Purity: 0.98
Chemical Name or Material:
N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Quantity:
10 mg
Molecular Formula:
C14H15N5
CAS:
923596-52-5
Target:
Cyclin-dependent Kinase Inhibitors
Purity:
0.98
Chemical Name or Material: N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Quantity: 50 mg
Molecular Formula: C14H15N5
CAS: 923596-52-5
Target: Cyclin-dependent Kinase Inhibitors
Purity: 0.98
Chemical Name or Material:
N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Quantity:
50 mg
Molecular Formula:
C14H15N5
CAS:
923596-52-5
Target:
Cyclin-dependent Kinase Inhibitors
Purity:
0.98
Chemical Name or Material: 8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8 ]naphthyridine
Quantity: 10 mg
Molecular Formula: C14H5F6N5O
CAS: 691868-88-9
Target: IFN-alpha/beta R2
Purity: 0.98
Chemical Name or Material:
8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8 ]naphthyridine
Quantity:
10 mg
Molecular Formula:
C14H5F6N5O
CAS:
691868-88-9
Target:
IFN-alpha/beta R2
Purity:
0.98