7116091
PF 04671536 hydrochloride
Potent and selective PDE8B/8A inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1305116-67-9
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Chemical Name or Material
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
Assay Percent Range
>98%
Formula Weight
Observed MW: 382.87
CAS
1305116-67-9
Molecular Formula
C14H18N8OS.HCl
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | PF 04671536 hydrochloride | Fischer Scientific | ₹ 41,026.02 | |
| | PF 04671536 hydrochloride | Fischer Scientific | ₹ 10,729.22 | |
 | 1305116-67-9 | 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-aminehydrochloride | A2B Chem | -- |
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Description
- Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively)
- Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets
- Increases glucose-dependent insulin secretion from human pacreatic islet cells
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Desiccate at Room Temperature
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Chemical Name or Material: 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
Assay Percent Range: >98%
Formula Weight: Observed MW: 382.87
CAS: 1305116-67-9
Molecular Formula: C14H18N8OS.HCl
Chemical Name or Material:
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 382.87
CAS:
1305116-67-9
Molecular Formula:
C14H18N8OS.HCl
Chemical Name or Material: 8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range: >98%
Formula Weight: Observed MW: 492.96
CAS: 1648863-90-4
Molecular Formula: C25H25ClN6O3
Chemical Name or Material:
8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 492.96
CAS:
1648863-90-4
Molecular Formula:
C25H25ClN6O3
Chemical Name or Material: 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 364.44
CAS: 1933533-18-6
Molecular Formula: C22H24N2O3
Chemical Name or Material:
4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 364.44
CAS:
1933533-18-6
Molecular Formula:
C22H24N2O3
Chemical Name or Material: 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
Assay Percent Range: >98%
Formula Weight: Observed MW: 296.39
CAS: 1234569-09-5
Molecular Formula: C13H20N4O2S
Chemical Name or Material:
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 296.39
CAS:
1234569-09-5
Molecular Formula:
C13H20N4O2S