54-941-0
Tocris Bioscience™ R 547
Manufacturer: Tocris Bioscience™
CAS Number: 741713-40-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 54-941-0-Each-of-1 | In Stock | ₹ 28,980.88 |
54-941-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,980.88
GST (18%): ₹ 5,216.558
Total Price: ₹ 34,197.438
Chemical Name or Material
[4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone
Quantity
10 mg
Formula Weight
441.45
CAS
741713-40-6
Molecular Formula
C18H21F2N5O4S
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences R547 >=98% (HPLC) | 741713-40-6 | MFCD09970629 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 14,044.67 | |
 | 741713-40-6 | R547 | A2B Chem | ₹ 2,139.00 - ₹ 49,795.92 |
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Description
- R 547 is a potent and selective CDK inhibitor (Ki values are 1, 2, 3, 46, 171 and 260 nM for CDK4/cyclin D1, CDK1/cyclin B, CDK2/cyclin E, GSK3α, CDK7/cyclin H and GSK3β)
- Exhibits no effect against a panel of >120 other kinases (Ki > 5,000 nM)
- Inhibits the proliferation of tumor cell lines independent of multidrug resistant status, or p53 status
- Suppresses retinoblastoma protein in tumor cells and xenografts
- Also inhibits tumor growth in the HCT116 human colorectal tumor xenograft model in nude mice
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
Show Difference
Chemical Name or Material: [4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone
Quantity: 10 mg
Formula Weight: 441.45
CAS: 741713-40-6
Molecular Formula: C18H21F2N5O4S
Purity: 98%
Chemical Name or Material:
[4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone
Quantity:
10 mg
Formula Weight:
441.45
CAS:
741713-40-6
Molecular Formula:
C18H21F2N5O4S
Purity:
98%
Chemical Name or Material: N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity: 25 mg
Formula Weight: 516.05
CAS: 1808951-93-0
Molecular Formula: C26H30ClN3O4S
Purity: 98%
Chemical Name or Material:
N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity:
25 mg
Formula Weight:
516.05
CAS:
1808951-93-0
Molecular Formula:
C26H30ClN3O4S
Purity:
98%
Chemical Name or Material: N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity: 5 mg
Formula Weight: 516.05
CAS: 1808951-93-0
Molecular Formula: C26H30ClN3O4S
Purity: 98%
Chemical Name or Material:
N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity:
5 mg
Formula Weight:
516.05
CAS:
1808951-93-0
Molecular Formula:
C26H30ClN3O4S
Purity:
98%
Chemical Name or Material: N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity: 25 mg
Formula Weight: 516.05
CAS: 1808948-28-8
Molecular Formula: C26H30ClN3O4S
Purity: 98%
Chemical Name or Material:
N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Quantity:
25 mg
Formula Weight:
516.05
CAS:
1808948-28-8
Molecular Formula:
C26H30ClN3O4S
Purity:
98%