7182961

Tocris Bioscience™ VU 0467485

Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant

Manufacturer: Fischer Scientific

CAS Number: 1451994-10-7

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Chemical Name or Material

5-Amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

CAS

1451994-10-7

Molecular Formula

C17H17FN4O2S

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
69-321-0
Tocris Bioscience™ VU 0467485
Fischer Scientific ₹ 24,613.90
69-325-0
Tocris Bioscience™ VU 0467485
Fischer Scientific ₹ 1,03,021.08
50-246-0837
eMolecules​ Medchem Express / VU0467485 / 5mg / 506403810 / HY-120184 / / 1451994-10-7 / MFCD31415018 / 360.410 / C17H17FN4O2S
eMolecules​ ₹ 15,113.32
CS-0077104
VU0467485
ChemScene ₹ 10,267.20 - ₹ 87,271.20

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Description

  • Potent and selective positive allosteric modulator of M4 receptor; potentiates activity of ACh at M4 (EC50 values are 26.6 and 78.8 nM at rat and human M4 receptors, respectively)
  • Exhibits selectivity for M4 over human and rat M1-3, 5, and a panel of 200 other pharmacological targets
  • Displays efficacy in a rat model of antipsychotic activity
  • Orally bioavailable and brain penetrant.

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Chemical Name or Material:
5-Amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

CAS:
1451994-10-7

Molecular Formula:
C17H17FN4O2S

Purity:
98%

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