7180133
Tocris™ LY 2033298
Selective positive allosteric modulator of M4 receptors.
Manufacturer: Fischer Scientific
CAS Number: 886047-13-8
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Chemical Name or Material
3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
CAS
886047-13-8
Molecular Formula
C13H14ClN3O2S
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ LY 2033298 | Fischer Scientific | ₹ 25,587.50 | |
| | Tocris™ LY 2033298 | Fischer Scientific | ₹ 98,968.00 | |
 | LY 2033298 | ChemScene | ₹ 18,957.00 - ₹ 34,621.00 | |
 | 886047-13-8 | 3-Amino-5-chloro-n-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide | A2B Chem | ₹ 21,004.00 - ₹ 36,668.00 |
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Description
- Selective positive allosteric modulator of M4 receptor (KB = 200 nM, α = 35); increases the potency of acetylcholine by 40-fold Exhibits no effect at hM1/3/5 receptors and a small effect at hM2 (KB = 1 μM α = 3.7) Potentiates other full and partial orthosteric agonists, including Carbachol, Oxotremorine-M, and McN-A343 Does not affect binding of antagonist NMS Active in vivo Antipsychotic
- α indicates the degree of allosteric enhancement when both orthosteric and allosteric sites are occupied (derived from the allosteric ternary complex model).
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
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Chemical Name or Material: 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
CAS: 886047-13-8
Molecular Formula: C13H14ClN3O2S
Purity: 98%
Chemical Name or Material:
3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
CAS:
886047-13-8
Molecular Formula:
C13H14ClN3O2S
Purity:
98%
Chemical Name or Material: N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide
CAS: 298684-44-3
Molecular Formula: C14H14ClNO2S
Purity: 98%
Chemical Name or Material:
N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide
CAS:
298684-44-3
Molecular Formula:
C14H14ClNO2S
Purity:
98%
Chemical Name or Material: Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate
CAS: 1928763-08-9
Molecular Formula: C19H24CIN3O3
Purity: 98%
Chemical Name or Material:
Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate
CAS:
1928763-08-9
Molecular Formula:
C19H24CIN3O3
Purity:
98%
Chemical Name or Material: 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide
CAS: 1945950-20-8
Molecular Formula: C23H25N5O4S3
Purity: 98%
Chemical Name or Material:
1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide
CAS:
1945950-20-8
Molecular Formula:
C23H25N5O4S3
Purity:
98%