7249495

Tocris Bioscience™ Hh-Ag1.5

Potent and high affinity Smo receptor agonist

Manufacturer: Fischer Scientific

CAS Number: 612542-14-0

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Chemical Name or Material

3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide

CAS

612542-14-0

Target

Smoothened

Molecular Formula

C28H26ClF2N3OS

Other Options

Image Product Name Manufacturer Price Range
78-071
Tocris Bioscience™ Hh-Ag1.5
Fischer Scientific ₹ 21,261.66
78-075
Tocris Bioscience™ Hh-Ag1.5
Fischer Scientific ₹ 68,875.80
50-226-1719
Medchemexpress LLC HY-124899 5mg , Hh-Ag1.5 CAS:612542-14-0 Purity:>98%
Medchemexpress LLC ₹ 35,036.82
50-247-5156
eMolecules​ Medchem Express / Hh-Ag1.5 / 5mg / 705860454 / HY-124899 / / 612542-14-0 / [null] / 526.040 / C28H26ClF2N3OS
eMolecules​ ₹ 48,264.40
AG80810
612542-14-0 | 3-Chloro-4,7-difluoro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide
A2B Chem ₹ 17,026.44 - ₹ 1,79,077.08

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Description

  • Hh-Ag1.5 is a potent and high affinity Hedgehog (Hh) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay)
  • It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells
  • Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Chemical Name or Material:
3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide

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612542-14-0

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Molecular Formula:
C28H26ClF2N3OS

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Molecular Formula:
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