7139262
ML 323
Potent and selective USP1-UAF1 allosteric inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1572414-83-5
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CAS
1572414-83-5
Molecular Formula
C23H24N6
Purity
98%
Synonym
5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine
Formula Weight
384.48
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | ML 323 | Fischer Scientific | ₹ 10,222.71 | |
| | ML 323 | Fischer Scientific | ₹ 39,203.59 | |
 | eMolecules Medchem Express / ML-323 / 5mg / 446268600 / HY-17543 / / 1572414-83-5 / MFCD28099817 / 384.487 / C23H24N6 | eMolecules | ₹ 8,312.15 | |
 | 1572414-83-5 | 2-(2-Isopropylphenyl)-5-methyl-N-{[4-(1,2,3-triazol-1-yl)phenyl]methyl}pyrimidin-4-amine | A2B Chem | ₹ 1,967.88 - ₹ 1,01,303.04 |
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Description
- Potent and selective allosteric inhibitor of USP1-UAF1 deubiquitinase complex (IC50 = 76 nM)
- Exhibits selectivity for USP1-UAF1 over a panel of enzymes, including other deuquitinating enzymes
- Inhibits deubiquitination of PCNA and FANCD2 and sensitizes cisplatin-resistant H596 cells to cell death induced by cisplatin (Cat
- No
- 2251) in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
CAS: 1572414-83-5
Molecular Formula: C23H24N6
Purity: 98%
Synonym: 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine
Formula Weight: 384.48
CAS:
1572414-83-5
Molecular Formula:
C23H24N6
Purity:
98%
Synonym:
5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine
Formula Weight:
384.48
CAS: 168398-02-5
Molecular Formula: C20H24N6O.2HCl
Purity: 98%
Synonym: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride
Formula Weight: 437.37
CAS:
168398-02-5
Molecular Formula:
C20H24N6O.2HCl
Purity:
98%
Synonym:
(2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride
Formula Weight:
437.37
CAS: 1873358-87-2
Molecular Formula: C23H15F7N2O4
Purity: 98%
Synonym: N-[2′-Fluoro-4′-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1′biphenyl]-4-yl]-2-nitrobenzeneacetamide
Formula Weight: 516.36
CAS:
1873358-87-2
Molecular Formula:
C23H15F7N2O4
Purity:
98%
Synonym:
N-[2′-Fluoro-4′-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1′biphenyl]-4-yl]-2-nitrobenzeneacetamide
Formula Weight:
516.36
CAS: 6336-34-1
Molecular Formula: C14H12N2O3
Purity: 98%
Synonym: 4,4′-Oxybis[benzamide]
Formula Weight: 256.26
CAS:
6336-34-1
Molecular Formula:
C14H12N2O3
Purity:
98%
Synonym:
4,4′-Oxybis[benzamide]
Formula Weight:
256.26