7116077

STF 118804

NAMPT Inhibitors

Manufacturer: Fischer Scientific

CAS Number: 894187-61-2

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Chemical Name or Material

4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide

Assay Percent Range

>98%

Formula Weight

Observed MW: 461.53

CAS

894187-61-2

Molecular Formula

C25H23N3O4S

Other Options

Image Product Name Manufacturer Price Range
52-072-5
STF 118804
Fischer Scientific --
52-075
STF 118804
Fischer Scientific --
50-245-2723
eMolecules​ Medchem Express / STF-118804 / 5mg / 446261848 / HY-12808 / / 894187-61-2 / MFCD14918065 / 461.540 / C25H23N3O4S
eMolecules​ ₹ 7,556.66

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Description

  • NAMPT inhibitor (nicotinamide phosphoribosyltransferase, visfatin, PBEF1); inhibits NAD+ synthesis from nicotinamide
  • Potently inhibits the viability of multiple B-cell acute lymphoplastic leukemia (B-ALL) cell lines (IC50 < 10 nM); induces apoptosis in MF-411 cells
  • Induces regression of ALL xenografts and eliminates leukemia stems cells from bone marrow in mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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7116077

NAMPT Inhibitors...


Chemical Name or Material:
4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 461.53

CAS:
894187-61-2

Molecular Formula:
C25H23N3O4S

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Assay Percent Range:
>99%

Formula Weight:
Observed MW: 428.48

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Molecular Formula:
C25H24N4O3

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Assay Percent Range:
>98%

Formula Weight:
Observed MW: 400.35

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Molecular Formula:
C20H15F3N4O2

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Chemical Name or Material:
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Assay Percent Range:
>99%

Formula Weight:
Observed MW: 415.45

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Molecular Formula:
C23H24F3N3O