7161620
Tocris Bioscience™ E 2012
γ-secretase modulator; Notch-sparing
Manufacturer: Fischer Scientific
CAS Number: 870843-42-8
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Chemical Name or Material
(3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone
Molecular Formula
C25H26FN3O2
Purity
98%
CAS
870843-42-8
Formula Weight
419.49
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ E 2012 | Fischer Scientific | ₹ 20,876.64 | |
| | Tocris Bioscience™ E 2012 | Fischer Scientific | ₹ 86,415.60 | |
 | eMolecules Medchem Express / E 2012 / 5mg / 446255027 / HY-10016 / / 870843-42-8 / MFCD11042274 / 419.500 / C25H26FN3O2 | eMolecules | ₹ 12,594.43 | |
 | E 2012 | ChemScene | ₹ 8,556.00 - ₹ 94,116.00 | |
 | 870843-42-8 | E-2012 | A2B Chem | ₹ 7,529.28 - ₹ 49,368.12 |
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Description
- Lowers Aβ40 and Aβ42 levels and increases Aβ37 levels, in vitro and in vivo Displays no effect on γ-secretase processing of Notch, EphA4 and EphB2
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone
Molecular Formula: C25H26FN3O2
Purity: 98%
CAS: 870843-42-8
Formula Weight: 419.49
Chemical Name or Material:
(3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone
Molecular Formula:
C25H26FN3O2
Purity:
98%
CAS:
870843-42-8
Formula Weight:
419.49
Chemical Name or Material: N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Molecular Formula: C26H30ClN3O4S
Purity: 98%
CAS: 1808948-28-8
Formula Weight: 516.05
Chemical Name or Material:
N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Molecular Formula:
C26H30ClN3O4S
Purity:
98%
CAS:
1808948-28-8
Formula Weight:
516.05
Chemical Name or Material: (5Z)-5-(5-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinepropanoic acid
Molecular Formula: C14H9ClN2O4S2
Purity: 98%
CAS: 1426138-42-2
Formula Weight: 368.82
Chemical Name or Material:
(5Z)-5-(5-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinepropanoic acid
Molecular Formula:
C14H9ClN2O4S2
Purity:
98%
CAS:
1426138-42-2
Formula Weight:
368.82
Chemical Name or Material: 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one
Molecular Formula: C22H25N3O2S
Purity: 98%
CAS: 924377-85-5
Formula Weight: 395.52
Chemical Name or Material:
1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one
Molecular Formula:
C22H25N3O2S
Purity:
98%
CAS:
924377-85-5
Formula Weight:
395.52