7161601
Tocris Bioscience™ AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 1941214-06-7
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Chemical Name or Material
7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide
Molecular Formula
C23H23FN6O2
Purity
98%
CAS
1941214-06-7
Formula Weight
434.47
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ AZ 5704 | Fischer Scientific | ₹ 59,649.01 | |
| | Tocris Bioscience™ AZ 5704 | Fischer Scientific | ₹ 15,582.19 | |
 | 1941214-06-7 | 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide | A2B Chem | -- |
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Description
- Potent and selective ATM kinase inhibitor (IC50 = 0.6 nM in an enzyme inhibition assay) Exhibits > 600-fold selectivity for ATM over other kinases Inhibits ATM kinase in an in vitro cellular assay (IC50 = 0.33 μM) Potentiates the antitumor effects of the topoisomerase 1 inhibitor irinotecan in tumor bearing, immunocompromised mice Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide
Molecular Formula: C23H23FN6O2
Purity: 98%
CAS: 1941214-06-7
Formula Weight: 434.47
Chemical Name or Material:
7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide
Molecular Formula:
C23H23FN6O2
Purity:
98%
CAS:
1941214-06-7
Formula Weight:
434.47
Chemical Name or Material: [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur
Molecular Formula: C26H19F5N6OS
Purity: 98%
CAS: 1448316-08-2
Formula Weight: 558.53
Chemical Name or Material:
[3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur
Molecular Formula:
C26H19F5N6OS
Purity:
98%
CAS:
1448316-08-2
Formula Weight:
558.53
Chemical Name or Material: 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride
Molecular Formula: C17H21N3.HCl
Purity: 98%
CAS: __
Formula Weight: 303.83
Chemical Name or Material:
5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride
Molecular Formula:
C17H21N3.HCl
Purity:
98%
CAS:
__
Formula Weight:
303.83
Chemical Name or Material: N-[2-(Dimethylamino)ethyl]-12-oxo-12 H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Molecular Formula: C21H20N4O2
Purity: 98%
CAS: 896705-16-1
Formula Weight: 360.41
Chemical Name or Material:
N-[2-(Dimethylamino)ethyl]-12-oxo-12 H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Molecular Formula:
C21H20N4O2
Purity:
98%
CAS:
896705-16-1
Formula Weight:
360.41