67-655-0

Tocris™ JTP 103237

Manufacturer: Fischer Scientific

CAS Number: 1883864-16-1

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Chemical Name or Material

7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine

Quantity

50 mg

Purity

98%

CAS

1883864-16-1

Molecular Formula

C24H29F3N6O

Other Options

Image Product Name Manufacturer Price Range
Tocris™ JTP 103237
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Tocris™ JTP 103237
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Description

  • Potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor (IC50 = 20 - 40 nM) Displays >7000-fold selectivity for human MOGAT2 over human DGAT2
  • Modulates intestinal lipid absorption in mice Decreases triglyceride, diacylglycerol and fatty acid synthesis in mouse model of fatty liver Chronic treatment decreases hepatic triglyceride content and body weight, and improves glucose tolerance in diet-induced obese mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C