74-981-0

Tocris Bioscience™ SPOP-i-6lc

Manufacturer: Tocris Bioscience™

CAS Number: 2136270-56-7

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Pack Size SKU Availability Price
Each of 1 74-981-0-Each-of-1 In Stock ₹ 29,689.32

74-981-0 - Each of 1

₹ 29,689.32

In Stock

Quantity

1

Base Price: ₹ 29,689.32

GST (18%): ₹ 5,344.078

Total Price: ₹ 35,033.398

Chemical Name or Material

1,5-Dihydro-2-imino-10-methyl-N-[2-(4-methyl-1-piperazinyl)ethyl]-5-oxo-1-[2-(2-thienyl)ethyl]-2 H-dipyrido[1,2-a:2 ',3 '-d]pyrimidine-3-carboxamide

Quantity

10 mg

Molecular Formula

C26H31N7O2S

CAS

2136270-56-7

Target

Ubiquitin Ligase (E3) Inhibitors

Purity

98%

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Description

  • SPOP-i-6lc is a selective SPOP E3 ubiquitin ligase inhibitor (IC50 = 2.1 μM and 3.5 μM, in A498 and OS-RC-2 cell lines, respectively)
  • In vitro , SPOP-i-6lc suppresses viability and proliferation of A498 and OS-RC-2 kidney cancer cell lines
  • SPOP-i-6lc leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma (ccRCC) cell lines.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Tocris Bioscience™

74-981-0

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Chemical Name or Material:
1,5-Dihydro-2-imino-10-methyl-N-[2-(4-methyl-1-piperazinyl)ethyl]-5-oxo-1-[2-(2-thienyl)ethyl]-2 H-dipyrido[1,2-a:2 ',3 '-d]pyrimidine-3-carboxamide

Quantity:
10 mg

Molecular Formula:
C26H31N7O2S

CAS:
2136270-56-7

Target:
Ubiquitin Ligase (E3) Inhibitors

Purity:
98%

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Supelco

74003

analytical standard...


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Supelco

74011

certified reference material, Trace...


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Sigma Aldrich

740241

97%...


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