75-901-0
Tocris Bioscience™ Pexidartinib
Manufacturer: Fischer Scientific
CAS Number: 1029044-16-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 75-901-0-Each-of-1 | In Stock | ₹ 13,535.59 |
75-901-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,535.59
GST (18%): ₹ 2,436.406
Total Price: ₹ 15,971.996
Chemical Name or Material
N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity
10 mg
Molecular Formula
C20H15ClF3N5
CAS
1029044-16-3
Target
Additional RTK Inhibitors
Purity
98%
Other Options
Related Products
Description
- Pexidartinib is a potent colony-stimulating factor-1 receptor (CSF-1R) tyrosine kinase inhibitor (IC50 = 20 nM)
- In the B16F10 mouse melanoma model, Pexidartinib reduces the systemic and local accumulation of macrophages without affecting Gr-1+ myeloid derived suppressor cells
- When combined with tumor-specific CD8 T cell immunotherapy, Pexidartinib promotes the control of tumor growth
- In the BRAFV600E-driven mouse melanoma model, Pexidartinib improves the efficacy of adoptive cell therapy with reduction of TIMs and an increase in tumor-infiltrating lymphocytes and T cells
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity: 10 mg
Molecular Formula: C20H15ClF3N5
CAS: 1029044-16-3
Target: Additional RTK Inhibitors
Purity: 98%
Chemical Name or Material:
N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity:
10 mg
Molecular Formula:
C20H15ClF3N5
CAS:
1029044-16-3
Target:
Additional RTK Inhibitors
Purity:
98%
Chemical Name or Material: N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity: 50 mg
Molecular Formula: C20H15ClF3N5
CAS: 1029044-16-3
Target: Additional RTK Inhibitors
Purity: 98%
Chemical Name or Material:
N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity:
50 mg
Molecular Formula:
C20H15ClF3N5
CAS:
1029044-16-3
Target:
Additional RTK Inhibitors
Purity:
98%
Chemical Name or Material: __
Quantity: __
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
__
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__
Chemical Name or Material: __
Quantity: __
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
__
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__