K1538

Thermo Scientific™ CellSensor™ NFAT bla HEK 293T Cell Line

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1538-Each-of-1 In Stock ₹ 9,05,224.80

K1538 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity

1 Vial

System Type

CellSensor™

Cell State

Dividing Cells

Product Line

CellSensor™

Target Entry

PKC, PKC and calcium pathway

Druggable Target

Signaling Pathway

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Description

  • The CellSensor™ NFAT-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into HEK 293T cells
  • Fluorescence activated cell sorting (FACS) was used to isolate clones responsive to stimulation of the NFAT pathway by PMA (Phorbol 12-Myristate 13-Acetate) and Thapsagargin (Thaps)
  • The cell line was validated for DMSO tolerance, cell number, stimulation time, substrate loading conditions, and EC50 concentration of Thaps at fixed concentration of PMA
  • The CellSensor™ NFAT-bla HEK 293T cell line responds to agonist treatment as expected from the literature and can be adapted for high-throughput screening (including coupling of receptors to the NFAT pathway) for agonists or antagonists with compound libraries
  • Candidate drugs can also be tested for dose response against this cell line
  • Academic and non-profit customers, please inquire for special pricing.

Compare Similar Items

Show Difference

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Thermo Scientific™

K1538

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

System Type:
CellSensor™

Cell State:
Dividing Cells

Product Line:
CellSensor™

Target Entry:
PKC, PKC and calcium pathway

Druggable Target:
Signaling Pathway

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Thermo Scientific™

K1539

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Assay Entry:
__

Content And Storage:
Shipping:Dry IceStorage:Liquid Nitrogen

Quantity:
2 x 106Cells

System Type:
GeneBLAzer™

Cell State:
Dividing Cells

Product Line:
GeneBLAzer™

Target Entry:
__

Druggable Target:
GPCR

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Thermo Scientific™

K1543

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Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.>b>Includes:• Tango™ GLP2R-bla U2OS cells• Tango™ GLP2R-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ GLP2R-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Quantity:
8 x 106Cells

System Type:
Tango™

Cell State:
Dividing Cells

Product Line:
GeneBLAzer™

Target Entry:
GLP2R

Druggable Target:
GPCR

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Thermo Scientific™

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• GeneBLAzer™ CCKAR-NFAT-bla HEK 293T cells• GeneBLAzer™ CCKAR-NFAT-bla HEK 293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CCKAR-NFAT-bla HEK 293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Quantity:
2 x 106Cells

System Type:
GeneBLAzer™

Cell State:
Dividing Cells

Product Line:
GeneBLAzer™

Target Entry:
CCKAR

Druggable Target:
GPCR