K1655

Thermo Scientific™ CellSensor™ ISRE-blaHEK293T Cell Line

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1655-Each-of-1 In Stock ₹ 9,41,620.00

K1655 - Each of 1

₹ 9,41,620.00

In Stock

Quantity

1

Base Price: ₹ 9,41,620.00

GST (18%): ₹ 1,69,491.60

Total Price: ₹ 11,11,111.60

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity

1 Vial

System Type

CellSensor™

Cell State

Dividing Cells

Product Line

CellSensor™

Target Entry

JAK/STAT (Type I IFN) pathway, TYK2, JAK1

Druggable Target

Signaling Pathway

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Description

  • Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease
  • The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway
  • The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE)
  • This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus
  • Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation
  • A dose response curve for this assay against interferon alpha is available in the validation packet
  • Academic and non-profit customers, please inquire for special pricing.

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Show Difference

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

System Type:
CellSensor™

Cell State:
Dividing Cells

Product Line:
CellSensor™

Target Entry:
JAK/STAT (Type I IFN) pathway, TYK2, JAK1

Druggable Target:
Signaling Pathway

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

System Type:
CellSensor™

Cell State:
Dividing Cells

Product Line:
CellSensor™

Target Entry:
JAK/STAT (GM-CSF, EPO, IL-3) pathway, JAK2, STAT5

Druggable Target:
Signaling Pathway

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

System Type:
CellSensor™

Cell State:
Dividing Cells

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CellSensor™

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Druggable Target:
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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

System Type:
CellSensor™

Cell State:
Dividing Cells

Product Line:
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Target Entry:
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Druggable Target:
Signaling Pathway