K1662
CellSensor™ CellSensor™ NFκB-blaTHP-1 Cell Line
Manufacturer: CellSensor™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1662-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity
1 vial
Type
Cell Line
System Type
CellSensor™
Cell State
Dividing Cells
Product Line
CellSensor™
Target Entry
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line
THP-1
Druggable Target
Signaling Pathway
Related Products
Description
- The CellSensor™ NFκB-bla THP-1 cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor kappa B (NFκB) response element stably integrated into THP-1 cells
- To obtain the cell line, the NFκB-bla construct was transduced into THP-1 cells by lentivirus
- Subsequent flow cytometry was used to isolate cells responsive to Tumor Necrosis Factor alpha (TNFα)
- The cell line was validated for DMSO tolerance, cell number, stimulation time, substrate loading time, and EC50 concentration of TNFα
- The CellSensor™ NFκB-bla THP-1 cell line is responsive to TNFα and can be used to probe NFκB signaling pathways, including those involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease
- This cell line can be adapted for high-throughput screening for agonists or antagonists with compound libraries
- Candidate drugs can be tested for dose response against this cell line.
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Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity: 1 vial
Type: Cell Line
System Type: CellSensor™
Cell State: Dividing Cells
Product Line: CellSensor™
Target Entry: TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line: THP-1
Druggable Target: Signaling Pathway
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity:
1 vial
Type:
Cell Line
System Type:
CellSensor™
Cell State:
Dividing Cells
Product Line:
CellSensor™
Target Entry:
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line:
THP-1
Druggable Target:
Signaling Pathway
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity: 1 Vial
Type: __
System Type: CellSensor™
Cell State: Dividing Cells
Product Line: CellSensor™
Target Entry: TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line: __
Druggable Target: Signaling Pathway
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity:
1 Vial
Type:
__
System Type:
CellSensor™
Cell State:
Dividing Cells
Product Line:
CellSensor™
Target Entry:
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line:
__
Druggable Target:
Signaling Pathway
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity: 1 Vial
Type: __
System Type: CellSensor™
Cell State: Dividing Cells
Product Line: CellSensor™
Target Entry: TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line: __
Druggable Target: Signaling Pathway
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity:
1 Vial
Type:
__
System Type:
CellSensor™
Cell State:
Dividing Cells
Product Line:
CellSensor™
Target Entry:
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line:
__
Druggable Target:
Signaling Pathway
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity: 1 Vial
Type: __
System Type: CellSensor™
Cell State: Dividing Cells
Product Line: CellSensor™
Target Entry: TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line: __
Druggable Target: Signaling Pathway
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity:
1 Vial
Type:
__
System Type:
CellSensor™
Cell State:
Dividing Cells
Product Line:
CellSensor™
Target Entry:
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
Cell Line:
__
Druggable Target:
Signaling Pathway