K1733
Thermo Scientific™ GeneBLAzer™ CRHR2-CRE-blaCHO-K1 Cells
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1733-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1733 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Accession Number
NM_001883.2
Cell State
Dividing Cells
Detection Method
Fluorescence
Gene Symbol
CRHR2
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Cell Line
CHO-K1
Druggable Target
GPCR
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application)
FRET
Population Status
Single Cell Clone Origin
Quantity
2 x 106Cells
Target Entry
CRHR2
System Type
GeneBLAzer™
Related Products
Description
- GeneBLAzer™ CRHR2-CRE- bla CHO-K1 cells contain the human Corticotropin Releasing Factor Receptor 2 (CRHR2) stably integrated into the CellSensor™ CRE- bla CHO-K1 cell line
- CellSensor™ CRE- bla CHO-K1 cells (Cat
- No
- K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element
- The GeneBLAzer™ CRHR2-CRE- bla CHO-K1 cells are functionally validated for Z' and EC 50 concentrations of CRF
- In addition, GeneBLAzer™ CRHR2-CRE- bla CHO-K1 cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary
- Corticotropin releasing factor is a 41-amino acid peptide that plays a role in the integration of autonomic, neuroendocrine, and behavioral responses to stress
- These effects are mediated through two receptor families, CRHR1 and CRHR2
- While CRF was originally isolated from the hypothalamus, where it was shown to be the primary neuroregulator mediating the hypothalamic-pituitary-adrenocortical stress axis, it has since been found to be widely distributed outside the hypothalamus throughout the central nervous system
- Presently, there are five distinct targets for CRF with unique pharmacology and localization
- These have been placed into three distinct classes, two of which are the G-protein-coupled receptors CRF1 (CRHR1) and CRF2 (CRHR2)
- Three functional splice variants have been identified for the mammalian CRHR2 receptor, although pharmacological characterization of these splice variants revealed no major differences between them
- For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
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Accession Number: NM_001883.2
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: CRHR2
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: CRHR2
System Type: GeneBLAzer™
Accession Number:
NM_001883.2
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
CRHR2
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells• GeneBLAzer™ CRHR2-CRE-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CRHR2-CRE-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
CRHR2
System Type:
GeneBLAzer™
Accession Number: NM_000710
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: BDKRB1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: BDKRB1
System Type: GeneBLAzer™
Accession Number:
NM_000710
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
BDKRB1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
BDKRB1
System Type:
GeneBLAzer™
Accession Number: NM_000738
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: M1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ M1-NFAT-blaCHO-K1 cells• GeneBLAzer™ M1-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ M1-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: M1
System Type: GeneBLAzer™
Accession Number:
NM_000738
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
M1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ M1-NFAT-blaCHO-K1 cells• GeneBLAzer™ M1-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ M1-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
M1
System Type:
GeneBLAzer™
Accession Number: NM_001526.2
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: HCRTR2
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: HCRTR2
System Type: GeneBLAzer™
Accession Number:
NM_001526.2
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
HCRTR2
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ HCRTR2-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
HCRTR2
System Type:
GeneBLAzer™