Combines fast reaction kinetics with very low non-specific binding for increased throughput and precision Applications include automated immunoassays, immunoprecipitation, and protein purification Streptavidin coating targets Biotinylated Molecules Compounds that are difficult to attach to particle surfaces by conventional means may be amenable to biotinylation Provides a high biotin-binding capacity along with a strong affinity for targeted, biotin labeled molecules The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer Two layers of magnetite are coated onto this core, resulting in faster magnetic response times The surface is blocked with a non-surfactant, non-protein based method, to help prevent non-specific binding of proteins