SynVivo SynTumour 3D cancer mode assay kit, microvascular network configuration, 8 um pillars

Description

• General description: 10 - SMN2 C002 SynTumor 50 μm gap, 8 μm height pillar barrier chips, 100 ft Tygon Tubing, 25 pack - Slide Clamps, 50 pack - 1 mL Syringe with Luer-Lok Tip, 50 pack - 24 Gauge Needle x 0.5 in longSynTumor is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically and morphologically realistic tumor microenvironment. The system enables (a) circulation in the microvasculature, (b) transport across the vessel walls, and (c) delivery to the tumors. Starting with scans of vascular networks incorporated with interstitial and tissue/tumor spaces, the SynTumor 3D tissue model creates an in-vitro tumor microenvironment akin to a viable histological slice.The SynTumor 3D Cancer model has the following benefits:Side by side architecture enables quantitative real time visualizationPhysiological leaky vasculature with engineered porous structuresMorphologically realistic in vivo based architecturePhysiologically realistic convective and diffusive transportMicrofluidic platform with ultra-low consumable volumes
• Linkage: LInk to Publicationsapplication text