01810
Cycloheximide
≥90% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 66-81-9
Synonym(S): 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 01810-1-G | In Stock | ₹ 13,444.65 |
| 5 G | 01810-5-G | In Stock | ₹ 30,872.90 |
01810 - 1 G
In Stock
Quantity
1
Base Price: ₹ 13,444.65
GST (18%): ₹ 2,420.037
Total Price: ₹ 15,864.687
biological source
microbial
Quality Level
200
Assay
≥90% (HPLC)
form
powder or crystals
color
white to light beige
antibiotic activity spectrum
fungiyeast
Mode of action
protein synthesis | interferes
InChI
1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChI key
YPHMISFOHDHNIV-FSZOTQKASA-N
Gene Information
human ... FKBP1A(2280) , PIN1(5300)
Other Options
Related Products
Description
- Application: Cyclohexamide (CHX) is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis[1][2] for detection of short-lived proteins, super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors. It has been shown to selectively clear macrophages in atherosclerotic plaques,[3] activate cumulus-free equine oocytes,[4] and to have neuroprotective properties.[5]
- Biochem/physiol Actions: Cycloheximide (CHX) is an antibiotic produced by Strptomyces sp.. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.
- Packaging: 1G, 5G
- Other Notes: Conditions for safe storage, including any incompatibilities. Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Chronic 2 - Muta. 2 - Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: microbial
Quality Level: 200
Assay: ≥90% (HPLC)
form: powder or crystals
color: white to light beige
antibiotic activity spectrum: fungiyeast
Mode of action: protein synthesis | interferes
InChI: 1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChI key: YPHMISFOHDHNIV-FSZOTQKASA-N
Gene Information: human ... FKBP1A(2280) , PIN1(5300)
biological source:
microbial
Quality Level:
200
Assay:
≥90% (HPLC)
form:
powder or crystals
color:
white to light beige
antibiotic activity spectrum:
fungiyeast
Mode of action:
protein synthesis | interferes
InChI:
1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChI key:
YPHMISFOHDHNIV-FSZOTQKASA-N
Gene Information:
human ... FKBP1A(2280) , PIN1(5300)
biological source: __
Quality Level: 300
Assay: __
form: __
color: __
antibiotic activity spectrum: __
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InChI: __
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Quality Level:
300
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antibiotic activity spectrum:
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Gene Information:
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Quality Level: __
Assay: __
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antibiotic activity spectrum: __
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biological source: __
Quality Level: 100
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InChI: 1S/O2Si/c1-3-2
InChI key: VYPSYNLAJGMNEJ-UHFFFAOYSA-N
Gene Information: __
biological source:
__
Quality Level:
100
Assay:
__
form:
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color:
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antibiotic activity spectrum:
__
Mode of action:
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InChI:
1S/O2Si/c1-3-2
InChI key:
VYPSYNLAJGMNEJ-UHFFFAOYSA-N
Gene Information:
__