81271

Polymyxin B solution

1 mg/mL in H2O, analytical standard

Manufacturer: Supelco

CAS Number: 1405-20-5

Select a Size

Pack Size SKU Availability Price
10 ML 81271-10-ML In Stock ₹ 8,086.28

81271 - 10 ML

₹ 8,086.28

In Stock

Quantity

1

Base Price: ₹ 8,086.28

GST (18%): ₹ 1,455.53

Total Price: ₹ 9,541.81

grade

analytical standard

Quality Level

100

concentration

1 mg/mL in H2O

technique(s)

HPLC: suitablegas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteriafungi

application(s)

pharmaceutical (small molecule)

format

single component solution

Mode of action

cell membrane | interferes

storage temp.

2-8°C

InChI

1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

Other Options

Image Product Name Manufacturer Price Range
50-255-1759
TOKU-E Polymyxin B ReadyMade™ Solution, 1405-20-5, 10 ML
TOKU-E ₹ 13,261.80
11-101-3053
Polymyxin B Solution, 1 mg/mL in Water, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 10,831.90
NC1001423
U.S. Pharmacopeia Polymyxin B sulphate | 1405-20-5 | 1301.6 g/mol | 200MG
U.S. Pharmacopeia ₹ 28,613.83
11-101-3054
Polymyxin B Sulfate Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 12,200.86
P19231G
Polymyxin B Sulfate, TCI America™
TCI America ₹ 13,321.69
50-186-3469
Sigma Aldrich Fine Chemicals Biosciences Polymyxin B sulfate United States Pharmacopeia (USP) Reference Standard | 1405-20-5 | 200MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 45,791.71
50-255-1766
TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 100 MU
TOKU-E ₹ 41,496.60
50-255-1765
TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 10 MU
TOKU-E ₹ 10,780.56
50-200-8925
Enzo Life Sciences Polymyxin B . sulfate (1g). CAS: 1405-20-5
Enzo Life Sciences ₹ 8,953.85
PHR1595
Polymyxin B Sulfate
Supelco ₹ 10,435.30

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Description

  • General description: Chemical structure: peptide
  • Application: Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
  • Biochem/physiol Actions: Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane. Mode of Resistance: The activity of Polymyxin B sulfate is inhibited by iron(II), Co(II), Mn(II) and Magnesium ions. Polymyxin B may also be incompaitible with other microbial agents, including amphoterecin, cephalothin sodium, cephasolin sodium and heparin sodium. Antimicrobial Spectrum: Has bactericidal action on most gram-negative bacilli, including E. Coli and on most fungi and gram-positive bacteria.
  • Preparation Note: This product is concentrated at 1 mg/mL in water, and should be stored at 2-8°C.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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grade:
analytical standard

Quality Level:
100

concentration:
1 mg/mL in H2O

technique(s):
HPLC: suitablegas chromatography (GC): suitable

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriafungi

application(s):
pharmaceutical (small molecule)

format:
single component solution

Mode of action:
cell membrane | interferes

storage temp.:
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InChI:
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

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