Description

• General description: Chemical structure: aminoglycoside
• Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
• Biochem/physiol Actions: Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.Antimicrobial Spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
• Packaging: 10ml
• Preparation Note: This product contains 1 mg/mL Streptomycin in 1 mM EDTA and should be stored at 2-8°C.
• Other Notes: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.