A4941

Activin A human

≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
5 μG A4941-5-μG In Stock ₹ 25,438.75
10 μG A4941-10-μG In Stock ₹ 30,245.05

A4941 - 5 μG

₹ 25,438.75

In Stock

Quantity

1

Base Price: ₹ 25,438.75

GST (18%): ₹ 4,578.975

Total Price: ₹ 30,017.725

biological source

human

Quality Level

200

recombinant

expressed in baculovirus infected insect cells

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

1-10 ng/mL ED50

mol wt

dimer 26 kDa (containing 116 amino acid residues βA subunits)

packaging

pkg of 10 μgpkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

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Description

  • General description: Activin A gene with two exons is mapped to human chromosome 2q35.[1] Activin A also known as inhibin α-subunit belongs to the TGF-β (transforming growth factor-β) superfamily of proteins[2] and its expression is exclusive to gonads, placenta and adrenal cortex.[1]
  • Application: Activin A human has been used as a constituent of modified barth′s saline used in in vitro induction of pronephros.[3] It has also been used as a constituent of Roswell Park memorial institute (RPMI) media to induce pancreatic differentiation of multipotent dermal fibroblasts in vitro.[4]
  • Biochem/physiol Actions: Activins play a vital role in the regulation of hormonogenesis, cellular homeostasis and differentiation programs.[5] Elevated expression of activin A and B leads to the loss of muscle mass. Both activin A and B have a potential to act as a serum markers of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).[2]
  • Physical form: Lyophilized from 0.2 μm filtered solution in 10 mM sodium citrate, pH 3.0.
  • Analysis Note: The biological activity is determined by its ability to inhibit the proliferation of mouse MPC-11 cells.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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≥95% (SDS-PAGE)

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lyophilized powder

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1-10 ng/mL ED50

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dimer 26 kDa (containing 116 amino acid residues βA subunits)

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