D2141
6-Diazo-5-oxo-L-norleucine
>95% (TLC), suitable for ligand binding assays
Manufacturer: Sigma Aldrich
CAS Number: 157-03-9
Synonym(S): (S)-2-Amino-6-diazo-5-oxocaproic acid, DON
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | D2141-5-MG | In Stock | ₹ 6,679.03 |
| 25 MG | D2141-25-MG | In Stock | ₹ 20,426.78 |
D2141 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 6,679.03
GST (18%): ₹ 1,202.225
Total Price: ₹ 7,881.255
Assay
>95% (TLC)
Quality Level
200
form
crystalline
technique(s)
ligand binding assay: suitable
color
light yellow
mp
145 °C
antibiotic activity spectrum
neoplastics
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-108357 5mg Medchemexpress, 6-Diazo-5-oxo-L-nor-Leucine CAS:157-03-9 Purity:>98% | Medchemexpress LLC | ₹ 13,475.70 | |
 | Medchemexpress LLC HY-108357 1mg Medchemexpress, 6-Diazo-5-oxo-L-nor-Leucine CAS:157-03-9 Purity:>98% | Medchemexpress LLC | ₹ 4,491.90 | |
 | Tocris Bioscience™ L-DON | Tocris Bioscience™ | -- | |
 | Sigma Aldrich Fine Chemicals Biosciences 6-Diazo-5-oxo-L-norleucine crystalline | 157-03-9 | MFCD00037218 | 5mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 7,794.52 | |
| | eMolecules Medchem Express / 6-Diazo-5-oxo-L-nor-Leucine / 1mg / 495799649 / HY-108357 / / 157-03-9 / MFCD00037218 / 171.156 / C6H9N3O3 | eMolecules | ₹ 6,297.22 | |
 | 6-Diazo-5-oxo-L-norleucine | Sigma Aldrich | ₹ 6,679.03 - ₹ 20,426.78 | |
 | 6-Diazo-5-oxo-L-nor-Leucine | ChemScene | ₹ 43,635.60 - ₹ 1,96,360.20 | |
 | 157-03-9 | L-Norleucine, 6-diazo-5-oxo- | A2B Chem | ₹ 3,850.20 - ₹ 2,11,162.08 |
Related Products
Description
- General description: Chemical structure: amino acid derivatives
- Application: 6-Diazo-5-oxo-L-norleucine (DON) has been used as an inhibitor of glutamine synthetase–glutamine(amide)-2-oxoglutarate aminotransferase.[1]
- Biochem/physiol Actions: 6-Diazo-5-oxo-L-norleucine (DON), a glutamine analogue, is used as an inhibitor to study the function, specificity and characteristics of cytidine triphosphate synthase 1(s) (CTPS1) and various glutaminase(s). DON is used to inhibit glutamine (GLN) flux between cells.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Assay: >95% (TLC)
Quality Level: 200
form: crystalline
technique(s): ligand binding assay: suitable
color: light yellow
mp: 145 °C
antibiotic activity spectrum: neoplastics
Mode of action: enzyme | inhibits
storage temp.: −20°C
SMILES string: N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
Assay:
>95% (TLC)
Quality Level:
200
form:
crystalline
technique(s):
ligand binding assay: suitable
color:
light yellow
mp:
145 °C
antibiotic activity spectrum:
neoplastics
Mode of action:
enzyme | inhibits
storage temp.:
−20°C
SMILES string:
N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
Assay: 99%
Quality Level: 200
form: liquid
technique(s): __
color: __
mp: __
antibiotic activity spectrum: __
Mode of action: __
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SMILES string: CCCNCCC
Assay:
99%
Quality Level:
200
form:
liquid
technique(s):
__
color:
__
mp:
__
antibiotic activity spectrum:
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Mode of action:
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storage temp.:
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SMILES string:
CCCNCCC
Assay: __
Quality Level: __
form: __
technique(s): __
color: __
mp: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __
Assay:
__
Quality Level:
__
form:
__
technique(s):
__
color:
__
mp:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
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Assay: 99%
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form: liquid
technique(s): __
color: __
mp: __
antibiotic activity spectrum: __
Mode of action: __
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SMILES string: CC(O)COCC(C)O.CC(O)COC(C)CO.CC(CO)OC(C)CO
Assay:
99%
Quality Level:
200
form:
liquid
technique(s):
__
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antibiotic activity spectrum:
__
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__
storage temp.:
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SMILES string:
CC(O)COCC(C)O.CC(O)COC(C)CO.CC(CO)OC(C)CO